Cailing Xu
12 Papers
Cailing Xu is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 4, co-authored 8 publications.
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Papers
NPASS database update 2023: quantitative natural product activity and species source database for biomedical research
Huijun Zhao,Yuan Yang,Shuaiqi Wang,Xuesong Yang,Kaicheng Zhou,Cailing Xu,Xuyao Zhang,Jiajun Fan,Dongyue Hou,Xingxiu Li,Ying Tan,Shanshan Wang,Xinyi Chu,Dongzhi Zhuoma,Fengying Zhang,Dianwen Ju,Xian Zeng,Yu Zong Chen +17 more
TL;DR: In this article , the authors describe an update of the NPASS natural product activity and species source database, which includes new data of ∼95 000 records of the composition/concentration values of ∼1 490 NPs/NP clusters in ∼390 species.
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TROP2-directed nanobody-drug conjugate elicited potent antitumor effect in pancreatic cancer
Cailing Xu,Min Zhu,Qian Wang,Jiajun Cui,Yuping Huang,Xiting Huang,Jing Huang,Junwei Gai,Guanghui Li,Peng Qiao,Xian Zeng,Dianwen Ju,Yakun Wan,Xuyao Zhang +13 more
TL;DR: HuNb_TROP2-HSA-MMAE has desirable affinity, internalization efficiency and antitumor activity and holds significant promise as a potential therapeutic option for the treatment of TROP2-positive pancreatic cancer.
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Cell Membrane-Derived Vesicle: A Novel Vehicle for Cancer Immunotherapy
TL;DR: The latest advances in cellular vesicles as vehicles for combinational cancer immunotherapy are systematically summarized with focuses on manufacturing processes, cell sources, therapeutic strategies and applications, providing an insight into the potential and existing challenges.
A novel nanobody-heavy chain antibody against Angiopoietin-like protein 3 reduces plasma lipids and relieves nonalcoholic fatty liver disease
Xiaozhi Hu,Jiajun Fan,Qianqian Ma,Lei Han,Zhonglian Cao,Cailing Xu,Jingyun Luan,Guangjun Jing,Yanyang Nan,Tao Wu,Ying Zhang,Hanqi Wang,Yuanzhen Zhang,Dianwen Ju +13 more
TL;DR: In this paper , a nanobody-heavy chain antibody (VHH-Fc) was used to inhibit ANGPTL3 for NAFLD treatment, which exhibited high affinities to the Angiopoietin-like protein 3 (ANGPTL), a critical lipid metabolism regulator.
GSDMD contributes to myocardial reperfusion injury by regulating pyroptosis
Xiaomiao Ye,Peng Zhang,Yuting Zhang,Jingyun Luan,Cailing Xu,Zhengyu Wu,Dianwen Ju,Wei Hu +7 more
TL;DR: It is revealed that GSDMD deficiency significantly alleviated the inflammatory response by regulating pyroptosis, reduced the infarct size and preserved cardiac function after MI/RI, thus providing a potential strategy for the treatment of myocardial reperfusion injury.
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