37 Papers
276 Citations
C. Orfila is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Kallikrein & Kidney. The author has an hindex of 12, co-authored 37 publications. Previous affiliations of C. Orfila include Centre national de la recherche scientifique.
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Papers
PPARγ Promotes Mannose Receptor Gene Expression in Murine Macrophages and Contributes to the Induction of This Receptor by IL-13
Agnès Coste,Marc Dubourdeau,Marie Denise Linas,Sophie Cassaing,Jean-Claude Lepert,Patricia Balard,Sandrine Chalmeton,José Bernad,C. Orfila,J. P. Seguela,Bernard Pipy +10 more
TL;DR: It is demonstrated that the MMR expression is induced in mouse peritoneal macrophages following exposure to PPARgamma ligands or to interleukine-13 (IL-13) via a PPAR Gamma signaling pathway, and suggested that endogenous PPARGamma ligand produced by phospholipase A2 activation may be an important regulator of MMR expression by IL-13.
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Abdominal fat tissue aspirate in human amyloidosis: light, electron, and immunofluorescence microscopic studies.
TL;DR: In this article, the results of abdominal fat tissue aspiration from 12 patients with biopsy-proved amyloidosis were investigated by different morphologic techniques, including light microscopy, after staining of the fat tissue with Congo red and examination with a polarizing microscope.
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IgA Nephropathy Complicating Diabetic Glomerulosclerosis
TL;DR: In patients with diabetes, the appearance of urinary abnormalities and/or deterioration in renal function altered the clinical history of diabetic nephropathy, and the disorders are clinically suggestive of the presence of nondiabetic renal disease and raised the possibility of another pathogenetic mechanism.
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Immunocytochemical characterization of lung macrophage surface phenotypes and expression of cytokines in acute experimental silicosis in mice.
TL;DR: The changes support the conclusion that an influx of the newly recruited and activated macrophage population, with a different phenotype, is induced by treatment during inflammation, and involve difference in functional activity and enhance TNF-α and IL-1β expression.
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Fanconi’s Syndrome, Kappa Light-Chain Myeloma, Non-Amyloid Fibrils and Cytoplasmic Crystals in Renal Tubular Epithelium
TL;DR: Data suggested the pathogenic role of the fibrils and crystals present in tubular epithelium in the tubular proximal syndrome of a 59-year-old woman with Fanconi's syndrome.
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