C M Sinton
Novartis
1 Papers
C M Sinton is an academic researcher from Novartis. The author has contributed to research in topics: Chemistry & Strychnine. The author has an hindex of 1, co-authored 1 publications.
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Papers
•Journal Article
CGS 19755, a selective and competitive N-methyl-D-aspartate-type excitatory amino acid receptor antagonist.
John Lehmann,Hutchison Alan J,S E McPherson,C Mondadori,Markus Schmutz,C M Sinton,C Tsai,Deborah E. Murphy,D J Steel,Michael Williams +9 more
TL;DR: CGS 19755 (cis-4-phosphonomethyl-2-piperidine carboxylic acid) was found to be a potent, stereospecific inhibitor of N-methyl-D-aspartate (NMDA)-evokes, but not KCl-evoked, [3H] acetylcholine release from slices of the rat striatum, suggesting a competitive interaction with NMDA-type receptors.
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