Background There is a lack of information about factors associated with in-hospital death and the impact of neurological complications on early outcome for patients with stroke treated in community settings. We investigated predictors for in-hospital mortality and attributable risks of death after ischemic stroke in a pooled analysis of large German stroke registers. Methods Stroke patients admitted to hospitals cooperating within the German Stroke Registers Study Group (ADSR) between January 1, 2000, and December 31, 2000, were analyzed. The ADSR is a network of regional stroke registers, combining data from 104 academic and community hospitals throughout Germany. The impact of patients' demographic and clinical characteristics, their comorbid conditions, and the treating hospital expertise in stroke care on in-hospital mortality was analyzed using Cox regression analysis. Attributable risks of death for medical and neurological complications were calculated. Results A total of 13 440 ischemic stroke patients were included. Overall in-hospital mortality was 4.9%. In women, higher age ( P P Conclusions Substantial differences were found in the impact of comorbid conditions on early outcome for men and women. Programs aiming at an improvement in short-term outcome after stroke should focus especially on a reduction of pneumonia and an early treatment of increased intracranial pressure.

https://jamanetwork.com/journals/jamainternalmedicine/articlepdf/217308/ioi30426.pdf

Predictors of In-Hospital Mortality and Attributable Risks of Death After Ischemic Stroke The German Stroke Registers Study Group

Background and Purpose— There is little information about early outcome after intravenous application of tissue-type plasminogen activator (tPA) for stroke patients treated in community-based setti...

Frequency of thrombolytic therapy in patients with acute ischemic stroke and the risk of in-hospital mortality: the German Stroke Registers Study Group.

ContextData are limited regarding the risks and benefits of thrombolytic therapy
for acute ischemic stroke outside of clinical trials.ObjectiveTo investigate predictors of in-hospital mortality in patients with
ischemic stroke treated with intravenous tissue plasminogen activator (tPA)
within a pooled analysis of large German stroke registers.Design and SettingProspective, observational cohort study conducted at 225 community and
academic hospitals throughout Germany cooperating within the German Stroke
Registers Study Group.PatientsA total of 1658 patients with acute ischemic stroke who were admitted
to study hospitals between 2000 and 2002 and were treated with tPA.Main Outcome MeasureIn-hospital mortality.ResultsOne hundred sixty-six patients (10%) who received tPA died during hospitalization,
with 67.5% of these deaths occurring within 7 days. Factors predicting in-hospital
death after tPA use were older age (for each 10-year increment in age, adjusted
odds ratio [OR], 1.6; 95% confidence interval [CI], 1.3-1.9) and altered level
of consciousness (adjusted OR, 3.4; 95% CI, 2.4-4.7). The overall rate of
symptomatic intracranial hemorrhage was 7.1% and increased with age. One or
more serious complications was observed in 27.2% of all patients and in 83.9%
of patients who died after tPA treatment. An inverse relation between the
number of patients treated with tPA in the respective hospital and the risk
of in-hospital death was observed (adjusted OR, 0.97; 95% CI, 0.96-0.99 for
each additional patient treated with tPA per year).ConclusionIn patients with ischemic stroke who are treated with tPA, disturbances
of consciousness and increasing age are associated with increased in-hospital
mortality.

/pdf/predictors-of-in-hospital-mortality-in-patients-with-acute-1sqh5zp02k.pdf

Predictors of in-hospital mortality in patients with acute ischemic stroke treated with thrombolytic therapy

Background
Stroke patients should be cared for in accordance with evidence-based guidelines. The extent of implementation of guidelines for the acute care of stroke patients in Germany has been unclear to date.

/pdf/the-quality-of-acute-stroke-care-an-analysis-of-evidence-k74obu9y5w.pdf

The Quality of Acute Stroke Care—an Analysis of Evidence-Based Indicators in 260 000 Patients

Hintergrund
Ziel der Sektion Notaufnahmeprotokoll der Deutschen Interdisziplinaren Vereinigung fur Intensivmedizin und Notfallmedizin (DIVI) war die Entwicklung eines Datensatzes zur Dokumentation von Notfallpatienten in zentralen Notaufnahmen (ZNA).

Nationaler Datensatz „Notaufnahme“

Background and purpose: Comparable, standardised data on the quality and efficiency of stroke care in Germany are lacking. The Arbeitsgemeinschaft Deutscher Schlaganfall-Register (ADSR - German Stroke Registries Study Group) has defined a Minimum DataSet for the evaluation of quality indicators of stroke treatment in Germany. Methods: The ADSR is a voluntary network of current regional stroke registries aiming at a standardisation in the use of stroke terminology and methods of data collection for German stroke databases. Currently six regional stroke registries are cooperating in the ADSR, combining data from about 18000 stroke patients in 110 hospitals annually. Results: In the design of the ADSR DataSet a modular approach was chosen. The ADSR Minimum DataSet was adapted for a wide use in different health care facilities. In addition to the Minimum DataSet an Advanced DataSet will be developed to document additional items of stroke care in specialised stroke centres. The ADSR DataSet collection will be completed by special Extended DataSets, designed for answering centre-specific and research questions. Conclusion: The ADSR Minimum DataSet allows a standardised assessment of stroke care in Germany. It is the first questionnaire that provides valid and reliable comparisons between different clinical settings as well as regional stroke databases. The ADSR Minimum DataSet defines core items for a future National German Health Report on stroke care.

Qualitätssicherung in der Schlaganfall-Behandlung: das Basismodul der Arbeitsgemeinschaft Deutscher Schlaganfall-Register (ADSR)

Background and purpose Comparable, standardised data on the quality and efficiency of stroke care in Germany are lacking. The Arbeitsgemeinschaft Deutscher Schlaganfall-Register (ADSR--German Stroke Registries Study Group) has defined a "Minimum DataSet" for the evaluation of quality indicators of stroke treatment in Germany. Methods The ADSR is a voluntary network of current regional stroke registries aiming at a standardisation in the use of stroke terminology and methods of data collection for German stroke databases. Currently six regional stroke registries are cooperating in the ADSR, combining data from about 18,000 stroke patients in 110 hospitals annually. Results In the design of the ADSR DataSet a modular approach was chosen. The ADSR "Minimum DataSet" was adapted for a wide use in different health care facilities. In addition to the "Minimum DataSet" an "Advanced DataSet" will be developed to document additional items of stroke care in specialised stroke centres. The ADSR DataSet collection will be completed by special "Extended DataSets", designed for answering centre-specific and research questions. Conclusion The ADSR "Minimum DataSet" allows a standardised assessment of stroke care in Germany. It is the first questionnaire that provides valid and reliable comparisons between different clinical settings as well as regional stroke databases. The ADSR "Minimum DataSet" defines core items for a future National German Health Report on stroke care.

[Quality assurance in treatment of stroke: basic module of the German Stroke Registry Study Group].

Monitoring quality of stroke care in Germany: the minimum DataSet of the German Stroke Registries Study Group (ADSR)

Handle everyday research tasks with reliable, citation-backed results

Your personal Research Agent to handle research tasks with citation-backed results

Popular Tasks used by Researchers

How can I help with your research?

Meet SciSpace

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

C Kugler

Author Tools

Chat about Author

Papers

Qualitätssicherung in der Schlaganfall-Behandlung: das Basismodul der Arbeitsgemeinschaft Deutscher Schlaganfall-Register (ADSR)

[Quality assurance in treatment of stroke: basic module of the German Stroke Registry Study Group].

Monitoring quality of stroke care in Germany: the minimum DataSet of the German Stroke Registries Study Group (ADSR)