19 Papers
287 Citations
C. Emde is an academic researcher from University Hospital of Lausanne. The author has contributed to research in topics: Ranitidine & Antrum. The author has an hindex of 10, co-authored 19 publications.
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Papers
Effects of ranitidine and cisapride on acid reflux and oesophageal motility in patients with reflux oesophagitis: a 24 hour ambulatory combined pH and manometry study.
W Inauen,C. Emde,B. Weber,David Armstrong,H U Bettschen,T Huber,U Scheurer,A. L. Blum,F Halter,H S Merki +9 more
TL;DR: The findings show that the 30% reduction of oesophageal acid exposure achieved by a conventional dose of ranitidine can be improved to more than 60% by combination with cisapride (20 mg twice daily), and combination of a histamine H2 receptor antagonist with a prokinetic agent may therefore provide an alternative treatment for reflux oesphagitis.
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Nocturnal oesophageal motor activity is dependent on sleep stage.
Fabiana Castiglione,C. Emde,David Armstrong,C. Schneider,Peter Bauerfeind,Georg Stacher,A. L. Blum +6 more
TL;DR: The results of this study suggest that there is no intrinsic oesophageal motor activity in the absence of a stimulatory input from the central nervous system and that the increased number of secondary contractions during REM sleep may be a result of an REM related increase in autonomic nervous system activity although a temporary decrease of efferent inhibitory influences cannot be ruled out.
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Reproducibility of ambulatory gastric pH recordings in the corpus and antrum. Effect of food, time, and electrode position.
T. Cilluffo,David Armstrong,Fabiana Castiglione,C. Emde,R. Galeazzi,J. J. Gonvers,A. L. Blum +6 more
TL;DR: The reproducibility of simultaneous, long-term, ambulatory gastric pH recordings in the antrum and corpus was investigated in nine healthy subjects who underwent three separate, 27-h gastric double pH-metries, and showed that non-meal daytime pH was reproducible in the corpus but not in the Antrum.
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Twenty-four-hour pattern of esophageal motility in asymptomatic volunteers
TL;DR: All subjects showed similar patterns of diurnal esophageal contractory activity determined partly by meal intake and partly by a characteristic clustering of nocturnal contractions that could not be explained by episodes ofNocturnal gastroesophageals reflux, and it may be speculated thatnocturnal contraction clusters are associated with rhythmic phenomena such as MMC or specific sleep stages.
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Does smoking interfere with the effect of histamine H2-receptor antagonists on intragastric acidity in man?
P. Bauerfeind,T. Cilluffo,Claus J. Fimmel,C. Emde,C. von Ritter,W Kohler,R Gugler,T Gasser,A. L. Blum +8 more
TL;DR: Smoking does not affect intragastric acidity in untreated volunteers and only slightly decreases the effectiveness of histamine H2-receptor antagonists on intragastsic acidity, which explains the unfavourable effect of smoking on healing of peptic ulcer in patients treated with these drugs.
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