C. Capini
Princess Alexandra Hospital
8 Papers
35 Citations
C. Capini is an academic researcher from Princess Alexandra Hospital. The author has contributed to research in topics: Immune system & Rheumatoid arthritis. The author has an hindex of 6, co-authored 8 publications. Previous affiliations of C. Capini include Temple University.
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Papers
CNS invasion by CD14+/CD16+ peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection
Tracy Fischer-Smith,Sidney Croul,Andrij E. Sverstiuk,C. Capini,Darryl Z. L'Heureux,Emmanuel G. Régulier,Max W. Richardson,Shohreh Amini,Susan Morgello,Kamel Khalili,Jay Rappaport +10 more
TL;DR: Higher levels of soluble CD14 (sCD14) were observed in patients with moderate-to-severe HIV dementia, suggesting the utility of sCD14 as a surrogate marker and sCDl4 may be useful for evaluating these conditions.
Antigen-specific suppression of inflammatory arthritis using liposomes.
C. Capini,Montree Jaturanpinyo,Montree Jaturanpinyo,Hsin-I Chang,Srinivas Mutalik,Srinivas Mutalik,Alice McNally,Shayna E. A. Street,Raymond J. Steptoe,Brendan O'Sullivan,Nigel M. Davies,Ranjeny Thomas +11 more
TL;DR: It is shown that egg phosphatidylcholine liposomes loaded with Ag and a lipophilic NF-κB inhibitor suppress preexisting immune responses in an Ag-specific manner and could be readily adapted to deliver Ags and inhibitors for Ag- specific suppression of other autoimmune and allergic diseases.
Immunogenicity of HIV-1 IIIB and SHIV 89.6P Tat and Tat toxoids in rhesus macaques: induction of humoral and cellular immune responses.
Max W. Richardson,Jyotika Mirchandani,Peter Silvera,Emmanuel G. Régulier,C. Capini,Paul M. Bojczuk,Jason Hu,Edward J. Gracely,Jean D. Boyer,Kamel Khalili,Jean-François Zagury,Mark G. Lewis,Jay Rappaport +12 more
TL;DR: Results suggest that with intravenous SHIV89.6P challenge in rhesus macaques, precipitous CD4+ T-cell decline overwhelms potentially protective immune responses, and Tat toxoid as an excellent candidate vaccine component is confirmed.
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Autoantibodies to TNFα in HIV-1 infection: prospects for anti-cytokine vaccine therapy
C. Capini,Max W. Richardson,Houria Hendel,Andrij E. Sverstiuk,Jyotika Mirchandani,Emmanuel G. Régulier,Kamel Khalili,Jean-François Zagury,Jay Rappaport +8 more
TL;DR: The production of anti-TNFalpha antibodies appears to be an adaptive response to HIV infection and suggests the potential utility of modified cytokine vaccines in the treatment of HIV infections as well as AIDS-related and unrelated autoimmune and CNS disorders.
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Feasibility, safety and clinical effects of a single intradermal administration of autologous tolerising dendritic cells exposed to citrullinated peptides in patients with rheumatoid arthritis
Ranjeny Thomas,Shayna E. A. Street,Nishta Ramnoruth,Helen Pahau,Soi Law,Marion E. G. Brunck,Claire Hyde,Brendan O'Sullivan,C. Capini,Ai Tran,Jack C. Ng,Sanjoy K. Paul +11 more
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