C. Brady
10 Papers
54 Citations
C. Brady is an academic researcher. The author has contributed to research in topics: Chlamydophila abortus & Toxoplasma gondii. The author has an hindex of 6, co-authored 9 publications.
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Papers
Detection and quantification of Toxoplasma gondii in ovine maternal and foetal tissues from experimentally infected pregnant ewes using real-time PCR
Jorge Gutiérrez,J. O’Donovan,E. J. Williams,A. Proctor,C. Brady,P.X. Marques,Sheila Worrall,Jarlath E. Nally,Máire C. McElroy,H. F. Bassett,D. J. Sammin,David Buxton,Stephen W. Maley,Bryan Markey +13 more
TL;DR: Results indicate that the cotyledonary component of the foetal membranes is the sample of choice for the diagnosis of T. gondii by rt-PCR, followed byfoetal lung and brain.
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Monitoring clinical outcomes, pathological changes and shedding of Chlamydophila abortus following experimental challenge of periparturient ewes utilizing the natural route of infection
Jorge Gutiérrez,E. J. Williams,J. O’Donovan,C. Brady,A. Proctor,P.X. Marques,Sheila Worrall,Jarlath E. Nally,Máire C. McElroy,H. F. Bassett,D. J. Sammin,Bryan Markey +11 more
TL;DR: Results indicate that C. abortus can be detected in a large proportion of animals during the first pregnancy after oral infection, however, this proportion is reduced at the subsequent breeding season, confirming the occurrence of a chronic low level persistent infection in post-abortion/lambing ewes.
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Distribution of Lesions in Fetal Brains Following Experimental Infection of Pregnant Sheep With Toxoplasma gondii
J. O’Donovan,A. Proctor,Jorge Gutiérrez,S. Worrell,Jarlath E. Nally,P.X. Marques,C. Brady,Máire C. McElroy,D. J. Sammin,David Buxton,Stephen W. Maley,H. F. Bassett,Bryan Markey +12 more
TL;DR: Histopathologic examination of transverse sections taken at 13 levels in the fetal brains revealed the presence of toxoplasmosis-related lesions in all 6 brains, but lesions were not randomly distributed.
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Identification of Immunologically Relevant Proteins of Chlamydophila abortus Using Sera from Experimentally Infected Pregnant Ewes
P.X. Marques,Puneet Souda,J. O’Donovan,Jorge Gutiérrez,E. J. Gutierrez,Sheila Worrall,Máire C. McElroy,A. Proctor,C. Brady,D. J. Sammin,H. F. Basset,Julian P. Whitelegge,B. E. Markey,Jarlath E. Nally +13 more
TL;DR: Serum samples collected from experimentally infected pregnant ewes reacted specifically with several antigens of EB as determined by one-dimensional (1-D) and 2-D gel electrophoresis; reactiveAntigens identified by mass spectrometry included the major outer membrane protein (MOMP), polymorphic outer membraneprotein (POMP, and macrophage infectivity potentiator (MIP) lipoprotein).
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Descriptive analysis of ovine mortality in sentinel sheep flocks in Ireland.
Gerard M. Murray,Seamus Fagan,Denise Murphy,John Fagan,Colm Ó Muireagain,Rebecca Froehlich-Kelly,Damien Barrett,Maresa Sheehan,Margaret Wilson,C. Brady,Frank Hynes,Shauna Farrell,John Moriarty,Rónan O Neill,Mícheál Casey +14 more
TL;DR: Comparisons with existing passive surveillance findings reflect some differences in the relative frequency of detection of certain categories of disease suggesting that sentinel flock surveillance could usefully supplement existing passive animal disease surveillance activities for ovine disease.