C Blanco-Duque
University of Oxford
19 Papers
17 Citations
C Blanco-Duque is an academic researcher from University of Oxford. The author has contributed to research in topics: Non-rapid eye movement sleep & Sleep deprivation. The author has an hindex of 4, co-authored 9 publications. Previous affiliations of C Blanco-Duque include Picower Institute for Learning and Memory & John Radcliffe Hospital.
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Papers
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes
Joel W. Blanchard,Leyla Anne Akay,Jose Davila-Velderrain,Djuna von Maydell,Hansruedi Mathys,Shawn M. Davidson,Audrey H. Effenberger,Chih-Yu Chen,Kristal M. Maner-Smith,Ihab Hajjar,Eric A. Ortlund,Michael Bula,Emre Agbas,Ayesha P. Ng,Xueqiao Jiang,Martin Kahn,C Blanco-Duque,Nicolas Lavoie,Liwang Liu,Ricardo Reyes,Yuan-Ta Lin,Tak Ko,Lea R'Bibo,William T. Ralvenius,David A. Bennett,Hugh P. Cam,Manolis Kellis,Li-Huei Tsai +27 more
TL;DR: In this article , a single-cell transcriptomics profiling of post-mortem human brains from APOE4 carriers compared with non-carriers was performed to gain more comprehensive insights into the impact of APOE-4 on the human brain.
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A role for the cortex in sleep-wake regulation.
L B Krone,T Yamagata,C Blanco-Duque,C Blanco-Duque,Mathilde C. C. Guillaumin,Mathilde C. C. Guillaumin,M C Kahn,M C Kahn,Vincent van der Vinne,Vincent van der Vinne,L E McKillop,Shu K. E. Tam,Stuart N. Peirson,Colin J. Akerman,Anna Hoerder-Suabedissen,Zoltán Molnár,Vladyslav V. Vyazovskiy +16 more
TL;DR: In this paper, a subset of neocortical layer 5 pyramidal and archicortical dentate gyrus granule cells were silenced by ablating SNAP25, which increased wakefulness and reduced rebound of electroencephalographic slow-wave activity after sleep deprivation, suggesting a role for the cortex in both vigilance state control and sleep homeostasis.
Myelin plasticity and behaviour-connecting the dots.
Malte Sebastian Kaller,Alberto Lazari,C Blanco-Duque,Cassandra Sampaio-Baptista,Heidi Johansen-Berg +4 more
TL;DR: Changes in white matter and myelin are associated with learning during adulthood across species across species and the causal link between myelin plasticity and behaviour remains elusive.
96
Absent sleep EEG spindle activity in GluA1 (Gria1) knockout mice: relevance to neuropsychiatric disorders.
Gauri Ang,L E McKillop,R. J. Purple,C Blanco-Duque,Stuart N. Peirson,Russell G. Foster,Paul Harrison,Rolf Sprengel,Kay E. Davies,Peter L. Oliver,David M. Bannerman,Vladyslav V. Vyazovskiy +11 more
TL;DR: A striking reduction of EEG power density including the spindle-frequency range during sleep in Gria1−/− mice is reported, providing a novel link between glutamatergic dysfunction and sleep abnormalities in a schizophrenia-relevant mouse model.
Waking experience modulates sleep need in mice
L Milinski,Simon P. Fisher,Nanyi Cui,L E McKillop,C Blanco-Duque,Gauri Ang,T Yamagata,David M. Bannerman,Vladyslav V. Vyazovskiy +8 more
TL;DR: In this paper, the effects of repetitive behaviors such as wheel running or performing a simple touchscreen task, with wakefulness dominated by novel object exploration, on sleep timing and EEG slow-wave activity (SWA) during subsequent NREM sleep were investigated.