C. Bennett
University of South Florida
5 Papers
14 Citations
C. Bennett is an academic researcher from University of South Florida. The author has contributed to research in topics: Allele & Allele frequency. The author has an hindex of 4, co-authored 5 publications.
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Papers
Inherited prion disease with 144 base pair gene insertion: 2. clinical and pathological features
John Collinge,Jeremy P Brown,J. Hardy,Michael Mullan,Martin N. Rossor,Harry F. Baker,T. J. Crow,R. Lofthouse,Mark Poulter,Rosalind M. Ridley,F. Owen,C. Bennett,G. Dunn,A. E. Harding,Niall Quinn,B. Doshi,G. W. Roberts,M. Honavar,I. Janota,Peter L. Lantos +19 more
TL;DR: The phenotype of inherited prion disease (PrP 144 bp insertion) is described, a large family with autosomal dominant segregation of presenile dementia, and other neurological and behavioural features is described.
198
Clinical features of early onset, familial Alzheimer's disease linked to chromosome 14
Michael Mullan,C. Bennett,Cecilia Figueredo,David J. Hughes,R. Mant,M J Owen,Andrew C. Warren,Melvin G. McInnis,Anne Marshall,Peter L. Lantos,John Collinge,Alison Goate,H. Houlden,Fiona Crawford +13 more
TL;DR: The clinical features and genetic analysis of a British pedigree with early onset AD in which neither the beta APP locus nor any other chromosome 21 locus segregates with the disease, but in which good evidence is seen for linkage on the long arm of chromosome 14.
12
Inherited prion disease with 144 base pair gene insertion. 1. Genealogical and molecular studies.
Mark Poulter,Harry F. Baker,C. D. Frith,M Leach,R. Lofthouse,Rosalind M. Ridley,T. Shah,Frank Owen,John Collinge,Jeremy P Brown,J. Hardy,Michael Mullan,A. E. Harding,C. Bennett,R. Doshi,T. J. Crow +15 more
TL;DR: The disease was found to be closely linked to a 144 bp insertion within the open reading frame of the prion protein (PrP) gene with a maximum LOD score of 11.02 at zero recombination.
Evidence that the APOE locus influences rate of disease progression in late onset familial Alzheimer`s disease but is not causative
C. Bennett,Fiona Crawford,Aaron Osborne,Patricia Diaz,Jonathan Hoyne,Robert Lopez,P Roques,Ranjan Duara,Martin N. Rossor,Michael Mullan +9 more
TL;DR: It is suggested that the APOE locus enhances the rate of progression of the disease process in otherwise predisposed individuals and that variation at this locus is not able in and of itself to cause the disease.