C. Bearden
7 Papers
1 Citations
C. Bearden is an academic researcher. The author has contributed to research in topics: Medicine & Copy-number variation. The author has an hindex of 1, co-authored 5 publications.
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Papers
Rare CNVs and phenome-wide profiling: a tale of brain-structural divergence and phenotypical convergence
J. Kopal,Kuldeep Kumar,K. Saltoun,Claudia Modenato,Clara Moreau,Sandra Martin-Brevet,Guillaume Huguet,Martineau Jean-Louis,Charles-Olivier Martin,Zohra Saci,Nadine Younis,Petra Tamer,Elise Douard,Anne M. Maillard,Borja Rodriguez-Herreros,Aurélie Pain,Sonia Richetin,Leila Kushan,A. Silva,Marianne Bm van den Bree,David J. Linden,M J Owen,Jeremy Hall,Sarah Lippé,Bogdan Draganski,Ida E. Sønderby,Ole A. Andreassen,David C. Glahn,Paul M. Thompson,C. Bearden,Sébastien Jacquemont,Danilo Bzdok +31 more
TL;DR: This population-level investigation established brain structural divergences and phenotypical convergences of CNVs, with direct relevance to major brain disorders, that are tied to similar phenotypic profiles across ∼1000 lifestyle indicators.
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Subcortical brain alterations in carriers of genomic copy number variants
Kuldeep Kumar,Claudia Modenato,Clara Moreau,C. Ching,A. Simon Harvey,Sandra Martin-Brevet,Guillaume Huguet,Martineau Jean-Louis,Elise Douard,Charles-Olivier Martin,Nadine Younis,Petra Tamer,Anne M. Maillard,Borja Rodriguez-Herreros,Aurélie Pain,Sonia Richetin,Leila Kushan,Dmitry Isaev,Kathryn I. Alpert,Anjanibhargavi Ragothaman,Jessica A. Turner,L. Wang,Tiffany C. Ho,Lianne Schmaal,A. Silva,V. Marianne,David J. Linden,Marie Owen,Jeremy Hall,Sarah Lippé,Guillaume Dumas,Bogdan Draganski,Boris A. Gutman,Ida E. Sønderby,Ole A. Andreassen,L. Schultz,Laura Almasy,David C. Glahn,C. Bearden,Paul M. Thompson,Sebastian Jacquemont +40 more
TL;DR: In this article , the authors investigated gross volume, and vertex level thickness and surface maps of subcortical structures in 11 different copy number variants and 6 different neurodevelopmental and psychiatric disorders including autism (ASD) and schizophrenia (SZ).
Analysis of diagnosis instability in electronic health records reveals diverse disease trajectories of severe mental illness
Juan Fernando de la Hoz,A. Arias,S. Service,M. Castano Ramirez,Ana M. Díaz-Zuluaga,Carme Gallego,S. Ruiz-Sánchez,Javier I. Escobar,Alex A. T. Bui,C. Bearden,V. Reus,Carlos López-Jaramillo,N. Freimer,Loes M. Olde Loohuis +13 more
TL;DR: The results underline the importance of considering longitudinal rather than cross-sectional diagnoses in psychiatric research and show how high-quality EHR data can contribute to global efforts to understand disease trajectories.
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The association between area-level residential instability and gray matter volume changes
Brian Ku,Jean Addington,C. Bearden,Kristin S. Cadenhead,Tyrone D. Cannon,Merlita Compton,Barbara A. Cornblatt,Benjamin G. Druss,Matcheri S. Keshavan,D. Mathalon,Thomas H. McGlashan,Diana O. Perkins,Larry J. Seidman,William Stone,Ming T. Tsuang,Scott W. Woods,Elaine F. Walker +16 more
TL;DR: It is hypothesized that greater ARI will be associated with reduced right posterior CMFG and rACC GMVs, which may be an important social environmental characteristic that adversely impacts brain regions related to schizophrenia.
Fetal Gene Regulatory Gene Deletions are Associated with Poor Cognition and Altered Cortical Morphology in Schizophrenia and Community-Based Samples
J. Forsyth,J. Zhu,A. Chavannes,Z. Trevorrow,M. Hyat,S. Sievertsen,S. Ferreira-Ianone,M. Conomos,K. Nuechterlein,R. Asarnow,M. Green,K. Karlsgodt,D. Perkins,T. Cannon,J. Addington,K. Cadenhead,B. Cornblatt,M. Keshavan,D. Mathalon,W. Stone,M. Tsuang,E. Walker,S. Woods,K. Narr,S. McEwen,C. Schleifer,C. Yee,C. Diehl,A. Guha,G. Miller,A. Alexander-Bloch,Jakob Seidlitz,R. Bethlehem,R. Ophoff,C. Bearden +34 more
TL;DR: This study examines the association between gene deletions, cognition, and cortical morphology in schizophrenia and community-based samples, finding links between fetal gene regulatory gene deletions and poor cognition and altered brain structure.