C. Antonello
University of Padua
23 Papers
158 Citations
C. Antonello is an academic researcher from University of Padua. The author has contributed to research in topics: DNA & Nucleic acid. The author has an hindex of 9, co-authored 23 publications.
Chat about Author
Papers
4'-Methyl derivatives of 5-MOP and 5-MOA: synthesis, photoreactivity, and photobiological activity.
Ornella Gia,Antonella Anselmo,Maria Teresa Conconi,C. Antonello,Eugenio Uriarte,Sergio Caffieri +5 more
TL;DR: Photoreaction experiments showed that, unlike 8-MOP (8-methoxypsoralen) and 5-Mop, both angular derivatives bind thymine and cytosine with the same efficiency, and biological activity studies revealed a good correlation with the extent of covalent photoaddition.
32
•Journal Article
A search for potential antitumor agents: biological effects and DNA binding of a series of anthraquinone derivatives.
TL;DR: The biological results suggest that the mode of complex formation plays a less relevant role than DNA binding efficiency, and that the polynucleotide as an important target for drug action, rather than a minor, subterminal interacting site, is indicated.
17
Photoreaction of psoralen derivatives with structurally organized DNA.
TL;DR: In this article, the DNA-photobinding process of a number of psoralen derivatives has been investigated using different nucleic acid structures, such as double helical DNA, nucleosomes, and chromatin under various ionic strength conditions.
16
Diethylaminoalkyloxycoumarin and -furocoumarin derivatives.
TL;DR: In this article, four series of diethylaminoalkoxy derivatives of coumarin and furocoumarin have been prepared, in order to study their complexing capacity with DNA, these compounds having a double possibility of interaction.
13
Synthesis and photobiological activity of new methylpsoralen derivatives
Ornella Gia,Eugenio Uriarte,Giuseppe Zagotto,Francarosa Baccichetti,C. Antonello,S. Marciani-Magno +5 more
TL;DR: The synthesis and the photobiological activity of two new derivatives of psoralen, congeners of the monofunctional linear furocoumarin 3,4'-dimethyl-8-MOP, indicate lack of specificity for particular sequences of the nucleic acid.
12