Byoung-Mog Kwon
Korea Research Institute of Bioscience and Biotechnology
215 Papers
1.6K Citations
Byoung-Mog Kwon is an academic researcher from Korea Research Institute of Bioscience and Biotechnology. The author has contributed to research in topics: Obovatol & Chemistry. The author has an hindex of 34, co-authored 215 publications. Previous affiliations of Byoung-Mog Kwon include Woosuk University & Korea University of Science and Technology.
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Papers
Development of Tripeptidyl Farnesyltransferase Inhibitors.
TL;DR: The first tripeptide inhibitors of farnesyltransferase with sub-micromolar inhibition activity was developed based on the fact that CVFM is not a substrate for FARTE.
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Patent
Novel pyrazole and benzoxazole-substituted pyridine derivatives or pharmaceutically acceptable salts thereof, preparation process for same, and pharmaceutical composition for prevention and treatment of disorders involving aberrant cell proliferation
Jong Sung Koh,Jongkook Lee,Sung Yun Cho,Sun-Young Han,Chong Ock Lee,Jae Wook Ryu,Kyung Chan Park,Dong Cho Han,Ha Jae Du,Song-Kyu Park,Hee Jung Jung,Byoung-Mog Kwon,Kyung Ho Yoo,Taebo Sim +13 more
- 10 Dec 2009
TL;DR: In this article, a pyrazole and benzoxazole-substituted pyridine derivatives or pharmaceutically acceptable salts thereof, a preparation process for same, and a pharmaceutical composition for preventing and treating disorders involving aberrant cell proliferation containing the same as active ingredients.
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Isolation of farnesyltransferase inhibitors from herbal medicines.
TL;DR: Evidence now exists that specific inhibitors of FPTase will have an antitumorigenic effect, and 2-hydroxycinnamaldehyde, rhombenone, and arteminolide are isolated as inhibitors ofFPTase.
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Biphenyl versus phenylpyridazine derivatives: the role of the heterocycle in a series of acyl-CoA:cholesterol acyl transferase inhibitors.
Arianna Gelain,Daniela Barlocco,Byoung-Mog Kwon,Tae-Sook Jeong,Kyung-Ran Im,Laura Legnani,L. Toma +6 more
TL;DR: The results support the essential role of the pyridazine nucleus in the reported ACAT inhibitors phenylpyridazines analogues.
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Patent
Pharmaceutical composition containing obovatol as an active ingredient for the prevention and treatment of neurodegenerative diseases
Byoung-Mog Kwon,Kwang-Hee Son,Dong Han,Ji-Min Lee,Kyoungho Suk,Su Hong,Jiyeon Ock +6 more
- 10 Apr 2006
TL;DR: In this article, a pharmaceutical composition, comprising obovatol as an active ingredient, for the prevention and treatment of neurodegenerative diseases has been proposed, having superior inhibitory activity against the production of neurotoxic nitric oxides.
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