https://hal-univ-rennes1.archives-ouvertes.fr/hal-01077996/document

Benzyl β-malolactonate polymers: a long story with recent advances

Practical synthesis of mumefural, a component of Japanese apricot juice concentrate

Nephrotoxicity Induced by the R- and S-Enantiomers of N-(3,5-Dichlorophenyl)-2-hydroxysuccinimide (NDHS) and Their Sulfate Conjugates in Male Fischer 344 Rats

Synthesis of the molecular hybrid inspired by Largazole and Psammaplin A

Enantiomerically pure N-(3,5-dichlorophenyl)-2-hydroxysuccinimides (NDHS) and N-(3,5-dichlorophenyl)-2-hydroxysuccinimide-O-sulfates (NSC) have been synthesized in our laboratory in order to address their selectively related nephrotoxic mechanism. The key step for NDHS synthesis is the intramolecular nucleophilic cyclization via the amide N-atom with retention of configuration of the original stereogenic center. The corresponding sulfate conjugates (R)-NSC and (S)-NSC were prepared by reaction of enantiomeric NDHS with chlorosulfonic acid at -78 °C.

Synthesis of Enantiopure N-(3,5-Dichlorophenyl)-2-hydroxysuccinimides (NDHS) and N-(3,5-Dichlorophenyl)-2-hydroxysuccinimide-O-sulfates (NSC)

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Synthesis of Enantiopure N-(3,5-Dichlorophenyl)-2-hydroxysuccinimides (NDHS) and N-(3,5-Dichlorophenyl)-2-hydroxysuccinimide-O-sulfates (NSC)