Bryan Elchert
Utah State University
7 Papers
233 Citations
Bryan Elchert is an academic researcher from Utah State University. The author has contributed to research in topics: Aminoglycoside & Glycorandomization. The author has an hindex of 5, co-authored 7 publications. Previous affiliations of Bryan Elchert include Southern Research Institute.
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Papers
Application of the synthetic aminosugars for glycodiversification: synthesis and antimicrobial studies of pyranmycin.
Bryan Elchert,Jie Li,Jinhua Wang,Yu Hui,Ravi Rai,Roger Ptak,Priscilla Ward,Jon Y. Takemoto,Mekki F. Bensaci,Cheng-Wei Tom Chang +9 more
TL;DR: Although the antibacterial activity of pyranmycins against aminoglycoside resistant bacteria is less than expected, the synthetic methodologies of utilizing a library of aminosugars can be a model for future studies of glycodiversification or glycorandomization.
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Pyranmycins, a Novel Class of Aminoglycosides with Improved Acid Stability: The SAR of d-Pyranoses on Ring III of Pyranmycin
TL;DR: The synthesis of a novel class of aminoglycosides, pyranmycins, is reported along with the structure activity relationship (SAR) of their antibacterial activity against Escherichia coli, which will lead to the future designs of p Pyranmycin against drug resistant bacteria.
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Synthesis of trehalose-based compounds and their inhibitory activities against Mycobacterium smegmatis.
Jinhua Wang,Bryan Elchert,Yu Hui,Jon Y. Takemoto,Mekki F. Bensaci,John Wennergren,Huiwen Chang,Ravi Rai,Cheng-Wei Tom Chang +8 more
TL;DR: The synthesis of a library of trehalose-based compounds has been accomplished, and their activities against Mycobacterium smegmatis have been determined, and a preliminary structure-activity relationship (SAR) is reported.
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Application of the Synthetic Aminosugars for Glycodiversification: Synthesis and Antimicrobial Studies of Pyranmycin.
Bryan Elchert,Jie Li,Jinhua Wang,Yu Hui,Ravi Rai,Roger Ptak,Priscilla Ward,Jon Y. Takemoto,Mekki F. Bensaci,Cheng-Wei Tom Chang +9 more
TL;DR: A divergent approach was employed for the synthesis of aminosugars, from which a novel library of aminoglycoside antibiotics (pyranmycins) was synthesized as mentioned in this paper.
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Studies of the stereoselective reduction of ketosugar (hexosulose)
TL;DR: In this article, the authors summarize the factors in controlling the stereoselective reduction of ketosugars, which are valuable in the synthesis of various carbohydrate derivatives, and combine their results and those reported in the literature.
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