Bruno Verhasselt
Ghent University Hospital
127 Papers
1.2K Citations
Bruno Verhasselt is an academic researcher from Ghent University Hospital. The author has contributed to research in topics: Biology & T cell. The author has an hindex of 35, co-authored 116 publications. Previous affiliations of Bruno Verhasselt include Cold Spring Harbor Laboratory & Catholic University of Leuven.
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Papers
Evaluation of the Seegene Allplex™ Respiratory Panel for diagnosis of acute respiratory tract infections
Stien Vandendriessche,Elizaveta Padalko,Elke Wollants,Charlotte Verfaillie,Bruno Verhasselt,Liselotte Coorevits +5 more
TL;DR: The Seegene AllplexTM Respiratory panel was retrospectively challenged using a collection of quality control samples (QCMD) and clinical samples previously analysed with validated routine methods and performed well for routine detection of important respiratory targets.
Porcine sialoadhesin (CD169/Siglec-1) is an endocytic receptor that allows targeted delivery of toxins and antigens to macrophages.
Peter Delputte,Hanne Van Gorp,Herman W. Favoreel,Inge Hoebeke,Iris Delrue,Hannah L. Dewerchin,Frank Verdonck,Bruno Verhasselt,Eric Cox,Hans Nauwynck +9 more
TL;DR: These data expand sialoadhesin functionality and show that it can function as an endocytic receptor, a feature that cannot only be misused by sialic acid carrying pathogens, but that may also be used for specific targeting of toxins or antigens to sialoadedhesin-expressing macrophages.
EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells
An De Weer,Joni Van der Meulen,Pieter Rondou,Tom Taghon,Torsten A. Konrad,Katleen De Preter,Pieter Mestdagh,Tom Van Maerken,Nadine Van Roy,Marta Jeison,Isaac Yaniv,Barbara Cauwelier,Lucien Noens,Hélène-Antoine Poirel,Peter Vandenberghe,Frédéric Lambert,Anne De Paepe,Maria Garcia Sanchez,María D. Odero,Bruno Verhasselt,Jan Philippé,J Vandesompele,Rotraud Wieser,Nicole Dastugue,Pieter Van Vlierberghe,Bruce Poppe,Frank Speleman +26 more
TL;DR: MIR449A is revealed as a crucial direct target of the MECOM locus protein EVI1 involved in the pathogenesis of MECom‐rearranged leukaemias and unravels NOTCH1 and BCL2 as important novel targets of MIR449 a.
Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell lines versus CD77+ B-cells reveals a distinct subset of differentially expressed miRNAs.
Pieter Van Vlierberghe,An De Weer,Pieter Mestdagh,Tom Feys,Katleen De Preter,Pascale De Paepe,Kathleen Lambein,Jo Vandesompele,Nadine Van Roy,Bruno Verhasselt,Bruce Poppe,Frank Speleman +11 more
TL;DR: The data suggest that miRNAs are implicated in the pathogenesis of Hodgkin lymphoma and prompt further investigations concerning their role in cHL.
One protein to rule them all: modulation of cell surface receptors and molecules by HIV Nef.
TL;DR: An extensive review of the knowledge gained so far on the modulation of expression of HIV-1, HIV-2 and SIV Nef protein is provided.