Bruno Hagenbuch
University of Kansas
168 Papers
1.8K Citations
Bruno Hagenbuch is an academic researcher from University of Kansas. The author has contributed to research in topics: Organic anion-transporting polypeptide & Organic anion transporter 1. The author has an hindex of 65, co-authored 156 publications. Previous affiliations of Bruno Hagenbuch include University of Missouri–Kansas City & University of Kansas Hospital.
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Papers
Cotransport systems for inorganic sulfate and phosphate in small intestine and renal proximal tubule.
Heini Murer,Gregory A. Ahearn,Martin Amstutz,Jürg Biber,Colin D.A. Brown,P. Gmaj,Bruno Hagenbuch,Kerstin Malmström,Ingvild Mohrmann,Matthias Mohrmann,G. Stange +10 more
TL;DR: In the mammalian renal proximal tubule and small intestine, inorganic phosphate and sulfate are absorbed by an active, saturable process and the transcellular movement of sulfate and phosphate can be considered as secondary active.
12
Organic anion transporting polypeptides in the hepatic uptake of PBDE congeners in mice.
TL;DR: The hypothesis that BDE47, BDE99, and BDE153 are substrates of mouse hepatic Oatps is tested and the importance of hepaticOatps for the liver accumulation of BDE 47 was confirmed using Oatp1a4-, and Oat p1b2-null mice.
12
Rapid normalization of hepatic glycogen metabolism in rats with long-term bile duct ligation after biliodigestive anastomosis
Lukas Krähenbühl,Bruno Hagenbuch,Simona Berardi,Markus Schäfer,Stephan Krähenbühl,Stephan Krähenbühl +5 more
TL;DR: Reduced activity and mRNA levels of glycogen synthase suggest that impaired glycogen synthesis is the principal mechanism for decreased hepatic glycogen stores in BDL rats.
11
Expression of sodium-independent organic anion uptake systems of skate liver in Xenopus laevis oocytes.
TL;DR: This study confirms that an organic anion transport system for chloride-dependent BSP uptake, with characteristics similar to rat liver, is already expressed in the liver of lower vertebrates and thus represents a phylogenetically old system.
11
Free Cholesterol Affects the Function and Localization of Human Na+/Taurocholate Cotransporting Polypeptide (NTCP) and Organic Cation Transporter 1 (OCT1)
Jessica Y. Idowu,Bruno Hagenbuch +1 more
TL;DR: It is demonstrated that increased cholesterol levels can impair NTCP and OCT1 function, suggesting that the free cholesterol content of the liver can alter bile acid and drug uptake into the liver.