Bruce Bernard

TL;DR: In this paper, an analyte detection device and method related to a portable instrument suitable for point-of-care analyses is described, which is capable of obtaining diagnostic information using cellular and particle-based analyses and may be used in conjunction with membrane-and/or particlebased analysis cartridges.

TL;DR: This new instrument displays outstanding analytical characteristics, and presents a limit of detection of approximately 500 spores when tested with Bacillus globigii (Bg), a commonly used simulant for Bacillus anthracis (Ba), with a total analysis time of only 5 min.

TL;DR: An analyte detection device comprises: a body; a porous membrane coupled to the body, a top member positioned at a spaced distance above the porous membrane such that a first cavity is formed between the top member and the porous membranes, wherein the top members covered at least a portion of the porous surface, and wherein one or more particles disposed in the first cavity, wherein each particle comprises a receptor configured to interact with the analyte, and where particles that interact with analyte undergo a detectable spectroscopic change as discussed by the authors.

TL;DR: In this article, the authors proposed a simple and affordable method for measuring CD4 cells that can be implemented in resource-scarce settings, which can be used to diagnose and treat HIV infection.