Bronte M. Corner
Newcastle University
2 Papers
Bronte M. Corner is an academic researcher from Newcastle University. The author has contributed to research in topics: Interferon & STAT2. The author has an hindex of 2, co-authored 2 publications.
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Papers
Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2.
Christopher J A Duncan,Christopher J A Duncan,Benjamin J. Thompson,Rui Chen,Gillian I. Rice,Florian Gothe,Florian Gothe,Dan F. Young,Simon C. Lovell,Victoria G. Shuttleworth,Vicky Brocklebank,Bronte M. Corner,Andrew J. Skelton,Vincent Bondet,Jonathan Coxhead,Darragh Duffy,Cécile Fourrage,John H. Livingston,Julija Pavaine,Julija Pavaine,Edmund Cheesman,Stephania Bitetti,Angela Grainger,Meghan Acres,Barbara A. Innes,Aneta Mikulasova,Ruyue Sun,Rafiqul Hussain,Ronnie Wright,Ronnie Wright,Robert Wynn,Mohammed Zarhrate,Leo A. H. Zeef,Katrina M Wood,Stephen M. Hughes,Claire L. Harris,Karin R. Engelhardt,Yanick J. Crow,Yanick J. Crow,Richard E. Randall,David J. Kavanagh,David J. Kavanagh,Sophie Hambleton,Sophie Hambleton,Tracy A Briggs,Tracy A Briggs +45 more
TL;DR: Observations reveal an essential in vivo function of STAT2 in the regulation of human IFNα/β signaling, providing concrete evidence of the serious pathological consequences of unrestrained IFN α/β activity and supporting efforts to target this pathway therapeutically in IFN-associated disease.
Long-term outcomes and response to treatment in diacylglycerol kinase epsilon nephropathy.
Vicky Brocklebank,Vicky Brocklebank,Gurinder Kumar,Alexander J. Howie,Jayanthi Chandar,David V. Milford,Janet Craze,Jonathan Evans,Eric Finlay,Michael Freundlich,Daniel P. Gale,Carol Inward,Martin Mraz,Caroline Jones,William Wong,Stephen D. Marks,John O. Connolly,Bronte M. Corner,Kate Smith-Jackson,Kate Smith-Jackson,Patrick R. Walsh,Patrick R. Walsh,Kevin J. Marchbank,Kevin J. Marchbank,Claire L. Harris,Claire L. Harris,Valerie Wilson,Edwin K.S. Wong,Michal Malina,Michal Malina,Sally Johnson,Sally Johnson,Neil S. Sheerin,Neil S. Sheerin,David J. Kavanagh,David J. Kavanagh +35 more
TL;DR: Analysis of pathological features reveals that DGKE mutations give an MPGN-like appearance to different extents, with but more often without changes in arterioles or arteries, suggesting that in individuals who currently receive eculizumab therapy it can be safely withdrawn.
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