The Global Alliance to Improve Outcomes in Acne published recommendations for the management of acne as a supplement to the Journal of the American Academy of Dermatology in 2003. The recommendations incorporated evidence-based strategies when possible and the collective clinical experience of the group when evidence was lacking. This update reviews new information about acne pathophysiology and treatment–such as lasers and light therapy–and relevant topics where published data were sparse in 2003 but are now available including combination therapy, revision of acne scarring, and maintenance therapy. The update also includes a new way of looking at acne as a chronic disease, a discussion of the changing role of antibiotics in acne management as a result of concerns about microbial resistance, and factors that affect adherence to acne treatments. Summary statements and recommendations are provided throughout the update along with an indication of the level of evidence that currently supports each finding. As in the original supplement, the authors have based recommendations on published evidence as much as possible.

New insights into the management of acne: An update from the Global Alliance to Improve Outcomes in Acne Group

https://www.jidonline.org/article/S0022-202X(15)34480-8/pdf

Prevalence, Severity, and Severity Risk Factors of Acne in High School Pupils: A Community-Based Study

Subcommittee Members: Dr. Alexander Nast, Berlin (Germany) Dr. Cristina Oprica, Stockholm (Sweden) Prof. Dr. Brigitte Dreno, Nantes (France) Mrs. Stefanie Rosumeck, Berlin (Germany) Dr. Vincenzo Bettoli, Ferrara (Italy) Prof. Dr. Berthold Rzany, Berlin (Germany) Prof. Dr. Klaus Degitz, Munich (Germany) Dr. Adel Sammain, Berlin (Germany) Mr. Ricardo Erdmann, Berlin (Germany) Dr. Thierry Simonart, Brussels (Belgium) Prof. Dr. Andrew Finlay, Cardiff (United Kingdom) Dr. Niels Kren Veien, Aalborg (Denmark) Prof. Dr. Ruta Ganceviciene, Vilnius (Lithuania) Dr. Maja Vurnek fivkovi , Zagreb (Croatia) Dr. Alison Layton, Harrogate (United Kingdom) Prof. Dr. Christos Zouboulis, Dessau (Germany) Dr. Jose Luis Lopez Estebaranz, Madrid (Spain) Prof. Dr. Falk Ochsendorf, Frankfurt (Germany) Prof. Dr. med. Harald Gollnick, Magdeburg (Germany)

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1468-3083.2011.04374.x

European Evidence‐based (S3) Guidelines for the Treatment of Acne

Importance
Acne vulgaris is the most common skin condition affecting late adolescents across the globe. Although prior studies have evaluated epidemiologic patterns of acne vulgaris in various ethnicities and regions, adequate understanding of the worldwide burden of the disease associated with patients in their late adolescence (15–19-year olds) remains lacking.

/pdf/the-epidemiology-of-acne-vulgaris-in-late-adolescence-3bom806wb8.pdf

The epidemiology of acne vulgaris in late adolescence.

Scientific advances are continually improving the knowledge of acne and contributing to the refinement of treatment options; it is important for clinicians to regularly update their practice patterns to reflect current standards. The Global Alliance to Improve Outcomes in Acne is an international group of dermatologists with an interest in acne research and education that has been meeting regularly since 2001. As a group, we have continuously evaluated the literature on acne. This supplement focuses on providing relevant clinical guidance to health care practitioners managing patients with acne, with an emphasis on areas where the evidence base may be sparse or need interpretation for daily practice.

Practical management of acne for clinicians: An international consensus from the Global Alliance to Improve Outcomes in Acne

INTRODUCTION In the past 25 years, numerous topical and systemic drugs have been developed for the treatment of acne vulgaris The voluminous amount of clinical trial information has become increasingly difficult for individual physicians to monitor Clinical trials are a science no different than any other aspect of medicine There has been improvement in the design and performance of clinical trials in the past several years Currently, most authoritative opinions fully support the need for studies to be performed under the CONSORT and Cochrane principles We accept that many studies have not been as rigorously performed in the past as trials done in 2002 But to discard such studies is inappropriate, because they were done well according to the standards of the time Thus, for the time being, clinical opinion, based in part on formal discussion among expert colleagues with an interest in acne and a logical analysis of the literature, is not unreasonable as the basis for a Consensus Recommendation Such recommendations highlight the indications for use of medications and the optimal approach to the management of specific clinical problems Overall, the goal is to provide a comprehensive overview of rational therapy, which can form the basis for more uniform therapeutic strategies throughout the world, enhanced patient compliance, and more effective use of healthcare resources Several sets of guidelines have been developed for the treatment of acne during the past decade, including a practice guideline for the Oral Treatment of Acne in France (1999), Canadian Acne Treatment Guidelines (1995), German Guidelines for Acne Treatment (2001), Treatment of Acne Vulgaris: Guidelines for Primary Care Physicians (1991), and Guidelines of Care for Acne Vulgaris from the American Academy of Dermatology (1990) However, advances in medicine occur relatively rapidly, and practice guidelines may be out of date shortly after they are issued Thus, there is a continuing need to update existing recommendations so that recent advances in therapy can be brought to the attention of physicians in a timely manner In recognition of this need, this supplement to the Journal of the American Academy of Dermatology has been developed by a panel of physicians and researchers in the field of acne, working together as a Global Alliance to Improve Outcomes in Acne The mission of this group is to develop consensus recommendations for the treatment of acne, which are evidence-based when possible, and which include input from numerous countries The members of the group represent a broad list of international dermatologists with a special interest in acne and reflect a wide range of experiences and opinions The activities of the group have been coordinated by Dimensional Healthcare, Inc, and funded by an educational grant from Galderma As might be expected, some of the physicians involved in the development of this document have past or current, direct or indirect financial

https://www.jaad.org/article/S0190-9622(03)01563-9/pdf

Management of Acne: A Report From a Global Alliance to Improve Outcomes in Acne

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Management of Acne: A Report From a Global Alliance to Improve Outcomes in Acne