34 Papers
65 Citations
Brian Wang is an academic researcher from University of North Texas Health Science Center. The author has contributed to research in topics: Medicine & Stroke. The author has an hindex of 16, co-authored 29 publications. Previous affiliations of Brian Wang include Nanyang Technological University.
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Papers
Coupling of neurogenesis and angiogenesis after ischemic stroke.
TL;DR: Evidence has shown a highly possible interplay or dependence between stroke-induced neurogenesis and angiogenesis, and elucidating the underlying mechanisms of this coupling will be of great importance, which will provide the basis for neurorestorative therapy.
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Age-related Impairment of Vascular Structure and Functions.
Xianglai Xu,Brian Wang,Changhong Ren,Changhong Ren,Jiangnan Hu,David A. Greenberg,Tianxiang Chen,Liping Xie,Kunlin Jin +8 more
TL;DR: This work will review morphological alterations of aging vessels in-depth, which includes the discussion of age-related microvessel loss and changes to vasculature involving the capillary basement membrane, intima, media, and adventitia as well as the accompanying vascular dysfunctions arising from these alterations.
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Glial scar formation occurs in the human brain after ischemic stroke.
TL;DR: These findings suggest that reactive gliosis and glial scar formation as seen in animal models of stroke are reflective of what occurs in the human brain after an ischemic injury.
Activated regulatory T cell regulates neural stem cell proliferation in the subventricular zone of normal and ischemic mouse brain through interleukin 10
Jixian Wang,Jixian Wang,Luokun Xie,Chenqi Yang,Changhong Ren,Kaijing Zhou,Brian Wang,Zhijun Zhang,Yongting Wang,Kunlin Jin,Guo-Yuan Yang +10 more
TL;DR: It is concluded that activated Tregs enhanced neural stem cell (NSC) proliferation in the subventricular zone (SVZ) of normal and ischemic mice; blockage of IL-10 abolished T Regs-mediated NSC proliferation in vivo and in vitro.
Timing and Dose Regimens of Marrow Mesenchymal Stem Cell Transplantation Affect the Outcomes and Neuroinflammatory Response After Ischemic Stroke
Liuqing Wang,Zhenzhen Lin,Hongxia Zhang,Bei Shao,Li Xiao,Hui-Gang Jiang,Qichuan Zhuge,Luokun Xie,Brian Wang,Dong-Ming Su,Dong-Ming Su,Kunlin Jin,Kunlin Jin +12 more
TL;DR: Intravenous transplantation of bone marrow mesenchymal stem cells had been documented to improve functional outcome after ischemic stroke, but the timing and appropriate cell number remain further to be optimized.
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