Brian D. Phillips
Japan Tobacco
5 Papers
158 Citations
Brian D. Phillips is an academic researcher from Japan Tobacco. The author has contributed to research in topics: IIf & Renal function. The author has an hindex of 4, co-authored 4 publications. Previous affiliations of Brian D. Phillips include University of North Carolina at Chapel Hill.
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Papers
Expression profile of leukocyte genes activated by anti-neutrophil cytoplasmic autoantibodies (ANCA)
Jia Jin Yang,Jia Jin Yang,Gloria A. Preston,Gloria A. Preston,David A. Alcorta,David A. Alcorta,Iwao Waga,Iwao Waga,William E. Munger,William E. Munger,Susan L. Hogan,Susan L. Hogan,Stephen B. Sekura,Stephen B. Sekura,Brian D. Phillips,Brian D. Phillips,Robin P. Thomas,Robin P. Thomas,J. Charles Jennette,J. Charles Jennette,Ronald J. Falk,Ronald J. Falk +21 more
TL;DR: The data indicate that leukocyte genes are activated in vitro by both ANCA Fc and ANCAF(ab')2 pathways and that in vitro activation mimics changes in circulating leukocytes of patients with ANCA disease.
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Target antigens for anti-neutrophil cytoplasmic autoantibodies (ANCA) are on the surface of primed and apoptotic but not unstimulated neutrophils.
Jiajin Yang,Robin Tuttle,Susan L. Hogan,J. G. Taylor,Brian D. Phillips,Ronald J. Falk,John Charles Jennette +6 more
TL;DR: The surface expression of ANCA antigens on quiescent, primed, and apoptotic neutrophils is investigated and it is hypothesized that ANCA can react in’vivo with primed but not quiedcent neutrophil, and remain on the surface of cells after they become apoptotic.
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Monitoring proteinase 3 antineutrophil cytoplasmic antibodies for detection of relapses in small vessel vasculitis.
TL;DR: The capture PR3-ANCA ELISA is a sensitive tool for the detection of relapses and may be superior to indirect immunofluorescence (IIF) and standard ELISA for the diagnosis of vasculitis.
ODP050 Oncocytic Adrenocortical Carcinoma Presenting with Hematuria
TL;DR: A 70-year-old female with a history of morbid obesity, hypertension, anxiety, GERD, tubular adenoma, hyperlipidemia, and lumbar radiculopathy came in to see her primary care for hematuria and back pain this paper .
Gene expression profiles of circulating leukocytes correlate with renal disease activity in IgA nephropathy.
Gloria A. Preston,Gloria A. Preston,Iwao Waga,Iwao Waga,David A. Alcorta,David A. Alcorta,Hitoshi Sasai,Hitoshi Sasai,William E. Munger,William E. Munger,Pamela Sullivan,Pamela Sullivan,Brian D. Phillips,Brian D. Phillips,J. Charles Jennette,J. Charles Jennette,Ronald J. Falk,Ronald J. Falk +17 more
TL;DR: Data indicate that leukocytes carry informative disease-specific markers of pathogenic changes in renal tissue, as reflected by serum creatinine and Creatinine clearance values.