Brennan Jackson
Northwestern University
6 Papers
10 Citations
Brennan Jackson is an academic researcher from Northwestern University. The author has contributed to research in topics: Medicine & Subclinical infection. The author has an hindex of 2, co-authored 2 publications.
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Papers
Gamma frequency sensory stimulation in mild probable Alzheimer’s dementia patients: Results of feasibility and pilot studies
Diane Chan,Ho-Jun Suk,Brennan Jackson,Noah Milman,Danielle Stark,Elizabeth B. Klerman,Erin G. Kitchener,Vanesa S. Fernandez Avalos,Gabrielle de Weck,Arit Banerjee,Sara D. Beach,Joel W. Blanchard,Colton Stearns,Aaron D. Boes,Brandt D. Uitermarkt,Phillip E. Gander,Matthew A. Howard,Eliezer J. Sternberg,Alfonso Nieto-Castañon,Sheeba Arnold Anteraper,Susan Whitfield-Gabrieli,Emery N. Brown,Edward S. Boyden,Bradford C. Dickerson,Li-Huei Tsai +24 more
TL;DR: In this article , a non-invasive Gamma ENtrainment using Sensory Stimulation (GENUS) at 40Hz was shown to reduce Alzheimer's disease (AD) pathology such as amyloid and tau levels, prevent cerebral atrophy, and improve behavioral testing performance in mouse models of AD.
Walking With Ears: Altered Auditory Feedback Impacts Gait Step Length in Older Adults
Tara Cornwell,Jane Woodward,Mengnan,Mary Wu,Brennan Jackson,Pamela E. Souza,Jonathan H. Siegel,Sumitrajit Dhar,Sumitrajit Dhar,Keith E. Gordon +9 more
- 16 Apr 2020
TL;DR: The results suggest that during a steady-state walking task, healthy older adults can maintain walking control without auditory feedback, and increases in step length observed during the Ear Plugs condition suggest that temporal auditory cues provide locomotor feedback that becomes increasingly valuable as balance deteriorates with age.
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Immediate and short-term effects of real-time knee adduction moment feedback on the peak and cumulative knee load during walking.
TL;DR: The findings support the real‐time pKAM visual feedback as a tool for individualized gait modification to reduce knee load and future studies to evaluate its effectiveness in persons with or at risk for medial knee osteoarthritis is warranted.
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Gamma sensory stimulation and effects on the brain
Martin Kahn,Diane Chan,Danying Wang,Ute Geigenmuller,C Blanco-Duque,Mitchell H. Murdock,Ho-Jun Suk,Brennan Jackson,Vikram Jakkamsetti,Emily Niederst,Emery N. Brown,E. Boyden,Thomas McHugh,Chinnakkaruppan Adaikkan,Annabelle C. Singer,Simon Hanslmayr,Li-Huei Tsai +16 more
TL;DR: It is suggested that the data in Soula et al are consistent with a neuronal response to 40 Hz, which further support with new data in humans, and the non-significant effects on amyloid are due to technical limitations of the study.
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Drug Development.
Diane Chan,Monica Zheng,Ute Geigenmuller,Dimitrios Pantazis,Andrew Becker,M. J. Quay,Erika Ruiz,Remi Philips,Xinran Zhang,Natalie Hahn,Samantha Yee,Brennan Jackson,Edward S. Boyden,Emery N Brown,Li-Huei Tsai,Guillaume Leclerc +15 more
Abstract: Non‐invasive gamma‐frequency light and sound stimulation at 40Hz has shown promise as a possible disease modifying therapeutic for the treatment of Alzheimer’s disease (AD). However, human neural substrates generating a gamma frequency response to Gamma Entrainment Using Sensory (GENUS) stimulation have never been shown. Here, we aim to show brain regions that generate gamma frequency oscillations in response to GENUS stimulation.