Brenda W.J.H. Penninx
VU University Amsterdam
1217 Papers
9.5K Citations
Brenda W.J.H. Penninx is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Anxiety & Medicine. The author has an hindex of 170, co-authored 1139 publications. Previous affiliations of Brenda W.J.H. Penninx include University of Amsterdam & University of Jyväskylä.
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Papers
Longitudinal Association Between Depression and Inflammatory Markers: Results From the Netherlands Study of Depression and Anxiety
Femke Lamers,Yuri Milaneschi,Johannes H Smit,Robert A. Schoevers,Gayle M. Wittenberg,Brenda W.J.H. Penninx +5 more
TL;DR: In this longitudinal study, cross-sectional and bidirectional longitudinal associations were found between depression and IL-6 levels, which underlines the importance of targeting inflammation pathways in the treatment of major depressive disorder.
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Late‐Life Anemia Is Associated with Increased Risk of Recurrent Falls
Brenda W.J.H. Penninx,S. M. F. Pluijm,Paul Lips,Richard J. Woodman,Kor Miedema,Jack M. Guralnik,Dorly J. H. Deeg +6 more
TL;DR: To examine whether anemia is associated with a higher incidence of recurrent falls, a large number of patients with a history of anemia were diagnosed with recurrent falls in the first year of follow-up.
Leptin Dysregulation Is Specifically Associated With Major Depression With Atypical Features: Evidence for a Mechanism Connecting Obesity and Depression
TL;DR: Among currently depressed patients, higher leptin was associated with key symptoms identifying the atypical MDD subtype, such as hyperphagia, increased weight, and leaden paralysis, strengthening the hypothesis of the involvement of leptin resistance.
185
Development and validation of a 30-item short adaptation of the Mood and Anxiety Symptoms Questionnaire (MASQ)
Klaas J. Wardenaar,Tineke van Veen,Erik J. Giltay,Edwin de Beurs,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx,Frans G. Zitman +6 more
TL;DR: A 30-item short adaptation of the MASQ is developed and validated, which is more suitable for large-scale psychopathology research and has a clearer factor structure, and is a valid instrument to assess dimensional aspects of depression and anxiety.
183
Genome-wide association for major depression through age at onset stratification: Major depressive disorder working group of the Psychiatric Genomics Consortium
Robert Power,Katherine E. Tansey,Henriette N. Buttenschøn,Sarah Cohen-Woods,Tim B. Bigdeli,Lynsey S. Hall,Zoltán Kutalik,S. Hong Lee,S. Hong Lee,Stephan Ripke,Stephan Ripke,Stephan Ripke,Stacy Steinberg,Alexander Teumer,Alexander Viktorin,Naomi R. Wray,Volker Arolt,Bernard T. Baune,Dorret I. Boomsma,Anders D. Børglum,Enda M. Byrne,Enrique Castelao,Nicholas John Craddock,Ian W. Craig,Udo Dannlowski,Udo Dannlowski,Ian J. Deary,Franziska Degenhardt,Andreas J. Forstner,Scott D. Gordon,Hans J. Grabe,Jakob Grove,Steven P. Hamilton,Caroline Hayward,Andrew C. Heath,Lynne J. Hocking,Georg Homuth,Jouke J. Hottenga,Stefan Kloiber,Jesper Krogh,Mikael Landén,Mikael Landén,Maren Lang,Douglas F. Levinson,Paul Lichtenstein,Susanne Lucae,Donald J. MacIntyre,Pamela A. F. Madden,Patrik K. E. Magnusson,Nicholas G. Martin,Andrew M. McIntosh,Christel M. Middeldorp,Yuri Milaneschi,Grant W. Montgomery,Ole Mors,Ole Mors,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Dale R. Nyholt,Hogni Oskarsson,Michael John Owen,Sandosh Padmanabhan,Brenda W.J.H. Penninx,Michele L. Pergadia,David J. Porteous,James B. Potash,Martin Preisig,Margarita Rivera,Margarita Rivera,Jianxin Shi,Stanley I. Shyn,Engilbert Sigurdsson,Johannes H. Smit,Blair H. Smith,Hreinn Stefansson,Kari Stefansson,Jana Strohmaier,Patrick F. Sullivan,Patrick F. Sullivan,Pippa A. Thomson,Thorgeir E. Thorgeirsson,Sandra Van der Auwera,Myrna M. Weissman,Gerome Breen,Cathryn M. Lewis +84 more
TL;DR: It is demonstrated that using additional phenotype data previously collected by genetic studies to tackle phenotypic heterogeneity in MDD can successfully lead to the discovery of genetic risk factor despite reduced sample size.
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