Braxton L. Jamison
University of Colorado Denver
8 Papers
Braxton L. Jamison is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: NOD mice & FOXP3. The author has an hindex of 3, co-authored 4 publications. Previous affiliations of Braxton L. Jamison include University of Colorado Boulder.
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Papers
Nanoparticles Containing an Insulin-ChgA Hybrid Peptide Protect from Transfer of Autoimmune Diabetes by Shifting the Balance between Effector T Cells and Regulatory T Cells.
Braxton L. Jamison,Tobias Neef,Andrew Goodspeed,Brenda Bradley,Rocky L. Baker,Stephen D. Miller,Kathryn Haskins +6 more
TL;DR: This work is the first to use a hybrid insulin peptide, or any neoepitope, to re-educate diabetogenic T cells and may have significant implications for the development of an Ag-specific therapy for type 1 diabetes patients.
Tolerogenic Delivery of a Hybrid Insulin Peptide Markedly Prolongs Islet Graft Survival in the Non-Obese Diabetic (NOD) Mouse.
Braxton L. Jamison,James E DiLisio,K. Scott Beard,Tobias Neef,Brenda J. Bradley,Jessica L. Goodman,Ronald G. Gill,Stephen D. Miller,Rocky L. Baker,Kathryn Haskins +9 more
TL;DR: It is established that tolerance induction with a hybrid insulin peptide can delay recurrent autoimmunity in NOD mice, which could inform the development of an Ag-specific therapy for T1D.
Tissue Crosstalk in T1D: Is Insulin Special?
TL;DR: Peptides such as insulin B:12-20 are released into circulation, where they can be directly and broadly presented by antigen-presenting cells throughout the lymphatic system.
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Induction of tolerance to a CD4 T cell hybrid insulin peptide epitope prolongs islet graft survival and suppresses autoreactive CD8 T cells
James E DiLisio,Braxton L. Jamison,Tobias Neef,Stephen D. Miller,Rocky L. Baker,Kathryn Haskins +5 more
TL;DR: In this article , the authors showed that 2.5HIP, a dominant CD4 T cell HIP epitope in the NOD mouse, can prolong islet graft survival in transplanted diabetic NOD mice.
An IL-2 mutein promotes Foxp3+ Treg-mediated suppression of dendritic cell activation in response to inflammatory stimuli
TL;DR: In this paper , the authors performed a phenotypic analysis of Treg and classical dendritic cells (DC) from IL-2 mutein-treated mice and found that Fc.Mut24 treatment increased CTLA-4 recycling/expression on Treg with a concurrent decrease in PD-1 expression specifically on effector regulatory T (eTreg) cells.