Brandon Narvaez
4 Papers
Brandon Narvaez is an academic researcher. The author has contributed to research in topics: Biology & Messenger RNA. The author has an hindex of 2, co-authored 3 publications.
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Papers
mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron
Matthew Gagne,Juan I. Moliva,Kathryn E. Foulds,Shayne Andrew,Barbara J. Flynn,Anne P. Werner,Danielle A Wagner,I-Ting Teng,Bob C. Lin,Christopher Brooks Moore,Nazaire Jean-Baptiste,Robin E. Carroll,Stephanie L. Foster,Mit Patel,Madison Ellis,Venkata Viswanadh Edara,Nahara Vargas Maldonado,Mahnaz Minai,Lauren McCormick,Christopher Cole Honeycutt,Bianca M. Nagata,Kevin W. Bock,Caitlyn N. M. Dulan,Jamilet Cordon,Dillon R. Flebbe,John Paul Todd,Elizabeth McCarthy,Laurent Pessaint,Alex Van Ry,Brandon Narvaez,Daniel Valentin,Anthony Cook,Alan Dodson,Katelyn Steingrebe,Saule Nurmukhambetova,Sucheta Godbole,Amy R. Henry,Farida Laboune,Jesmine Roberts-Torres,Cynthia G. Lorang,Shivani G. Amin,Jessica F. Trost,M. Naisan,Manjula Basappa,J. B. Willis,Lingshu Wang,Wei Shi,Nicole A. Doria-Rose,Yi Zhang,Eun Sung Yang,Kwanyee Leung,Sijy O'Dell,R. Schmidt,Adam S. Olia,Cuiping Liu,Darcy R. Harris,Gwo-Yu Chuang,Guillaume Stewart-Jones,Isabella Renzi,Yen-Ting Lai,Agata Malinowski,Kai Wu,John R. Mascola,Andrea Carfi,Peter D. Kwong,Darin K. Edwards,Mark A. Lewis,Hanne Andersen,Kizzmekia S. Corbett,Martha Nason,Adrian B. McDermott,Mehul S. Suthar,Ian N. Moore,Mario Roederer,Nancy J. Sullivan,Daniel C. Douek,Robert A. Seder +76 more
TL;DR: In this article , the authors showed that boosting with Omicron-matched vaccines would enhance protection, but it is unclear whether boosting with omicron matched vaccines would improve protection.
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A Recombinant Subunit Vaccine Induces a Potent, Broadly Neutralizing, and Durable Antibody Response in Macaques against the SARS-CoV-2 P.1 (Gamma) Variant
Albert To,Teri Ann S. Wong,Michael M. Lieberman,Karen S. Thompson,Aquena H. Ball,Laurent Pessaint,Jack Greenhouse,Nisrine Daham,Anthony Cook,Brandon Narvaez,Zackery Flinchbaugh,Alex Van Ry,Jake Yalley-Ogunro,Hanne Andersen Elyard,Chih-Yun Lai,Oreola Donini,Axel T. Lehrer +16 more
TL;DR: The results demonstrate that a properly dosed and adjuvanted recombinant subunit vaccine can provide protective immunity against circulating VOCs for at least three months, and indicate that a higher antigen dose is required to provide durable protection against disease as vaccine immunity wanes.
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mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits comparable B cell expansion, neutralizing antibodies and protection against Omicron
Matthew Gagne,Juan I. Moliva,Kathryn E. Foulds,Shayne Andrew,Barbara J. Flynn,Anne P. Werner,Danielle A Wagner,I-Ting Teng,Bob C. Lin,Christopher Brooks Moore,Nazaire Jean-Baptiste,Robert B. Carroll,Stephanie L. Foster,Mit Patel,Madison Ellis,Venkata Viswanadh Edara,Nahara Vargas Maldonado,Mahnaz Minai,Lauren McCormick,Christopher Cole Honeycutt,Bianca M. Nagata,Kevin W. Bock,Caitlyn N. M. Dulan,Jamilet Cordon,John Paul Todd,Elizabeth McCarthy,Laurent Pessaint,Alex Van Ry,Brandon Narvaez,Daniel Valentin,Anthony Cook,Alan Dodson,Katelyn Steingrebe,Dillon R. Flebbe,Saule Nurmukhambetova,Sucheta Godbole,Amy R. Henry,Farida Laboune,Jesmine Roberts-Torres,Cynthia G. Lorang,Shivani G. Amin,Jessica F. Trost,M. Naisan,Manjula Basappa,J. B. Willis,Lingshu Wang,Wei Shi,Nicole A. Doria-Rose,Adam S. Olia,Cuiping Liu,Darcy R. Harris,Andrea Carfi,John R. Mascola,Peter D. Kwong,Darin K. Edwards,Hanne Andersen,Mark A. Lewis,Kizzmekia S. Corbett,Martha Nason,Adrian B. McDermott,Mehul S. Suthar,Ian N. Moore,Mario Roederer,Nancy J. Sullivan,Daniel C. Douek,Robert A. Seder +65 more
TL;DR: An SARS-CoV-2 Omicron boost may not provide greater immunity or protection compared to a boost with the current mRNA-1273 vaccine.
Strong immunogenicity & protection in mice with PlaCCine: A COVID-19 DNA vaccine formulated with a functional polymer
Subeena Sood,Majed Matar,Jessica Kim,Meredyth D Kinsella,Kempaiah Rayavara,Olivia Signer,John Henderson,Joseph Rogers,Bhavna Chawla,Brandon Narvaez,Alex Van Ry,Swagata Kar,Austin Arnold,Jennifer Rice,Alanna M. Smith,Daishui Su,J. Sparks,C. L. Goff,Jean D. Boyer,Khursheed Anwer +19 more
TL;DR: Findings suggest that PlaCCine DNA vaccines are effective and stable and further development against emerging SARS-CoV-2 variants is warranted.