Brad A. Hobson
University of California, Davis
16 Papers
84 Citations
Brad A. Hobson is an academic researcher from University of California, Davis. The author has contributed to research in topics: Status epilepticus & Medicine. The author has an hindex of 9, co-authored 11 publications. Previous affiliations of Brad A. Hobson include Oregon State University.
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Papers
Editor's Highlight: Spatiotemporal Progression and Remission of Lesions in the Rat Brain Following Acute Intoxication With Diisopropylfluorophosphate.
Sílvia Sisó,Brad A. Hobson,Danielle J Harvey,Donald A. Bruun,Douglas J. Rowland,Joel R. Garbow,Pamela J. Lein +6 more
TL;DR: These findings parallel descriptions of neuropathology in preclinical models of acute intoxication with OP nerve agents, and other seizurogenic chemicals, suggesting conserved mechanisms of pathology downstream of chemical-induced SE.
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Genome‐wide screening of alpha‐tocopherol sensitive genes in heart tissue from alpha‐tocopherol transfer protein null mice (ATTP−/−)
TL;DR: The present data identifies novel classes of AT sensitive genes in heart tissue with no significant change in the expression of classical antioxidant genes in ATTP−/− as compared to ATTP+/+ mice.
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From the Cover: MagneticResonance Imaging Reveals Progressive Brain Injury in Rats Acutely Intoxicated With Diisopropylfluorophosphate.
Brad A. Hobson,Sílvia Sisó,Douglas J. Rowland,Danielle J Harvey,Donald A. Bruun,Joel R. Garbow,Pamela J. Lein +6 more
TL;DR: The interanimal and interregional variations observed in lesion severity and progression, coupled with potential reinjury following spontaneous recurrent seizures, underscore the advantages of using in vivo imaging to longitudinally monitor neuropathology and, ultimately, therapeutic response, following acute OP intoxication.
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Zinc transporter expression in zebrafish (Danio rerio) during development.
Emily Ho,Stephanie R. Dukovcic,Brad A. Hobson,Carmen P. Wong,Galen W. Miller,Karin Hardin,Maret G. Traber,Robert L. Tanguay +7 more
TL;DR: The results suggest that zebrafish is an effective model organism to study the effects of zinc deficiency and further investigation is underway to identify possible molecular pathways that are dysregulated with maternal zinc deficiency.
A magnetic resonance imaging study of early brain injury in a rat model of acute DFP intoxication
Brad A. Hobson,Douglas J. Rowland,Suangsuda Supasai,Danielle J Harvey,Pamela J. Lein,Joel R. Garbow +5 more
TL;DR: The results imply that the timing of therapeutic intervention for attenuating brain injury following OP intoxication may be regionally dependent, and that longitudinal assessment of OP‐induced damage by MRI may be a powerful tool for assessing therapeutic response.
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