Börje Cronholm
Karolinska Institutet
11 Papers
459 Citations
Börje Cronholm is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Nortriptyline & Endogenous depression. The author has an hindex of 10, co-authored 11 publications.
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Papers
Relationship between plasma level and therapeutic effect of nortriptyline.
TL;DR: Monitoring plasma levels may be a way to increase the efficacy of treatment with these drugs, because the large individual variation in the pharmacokinetics of the tricyclic antidepressants makes prediction of plasma level from dosage in a given individual virtually impossible without knowledge of rate of elimination and apparent volume of distribution.
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Correlation of subjective side effects with plasma concentrations of nortriptyline.
TL;DR: Very high plasma levels of nortriptyline should presumably be avoided, since there is no evidence that they are needed for therapeutic effect and they are potentially harmful, but in any given patient the plasma level tended to be constant over a period of time.
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Memory functions in endogenous depression before and after electroconvulsive therapy.
Börje Cronholm,Jan-Otto Ottosson +1 more
TL;DR: Several investigations into the ability of an individual to learn new material after electroconvulsive therapy (ECT) have shown that, compared with the pretreatment state, there is impaired function for at least one day after a course of treatment, and that one week or more after the end of the therapy, a return to pretreatment levels or even improvement is observed.
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The experience of memory function after electroconvulsive therapy.
Börje Cronholm,Jan-Otto Ottosson +1 more
TL;DR: It is reasonable to assume that the varying complaints of impaired memory, at least in part, reflect true disturbances of memory abilities, and that patients who have gained an obvious release from emotional distress comparatively seldom complain of memory disturbances after E.C.T.
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Differential effects on suicidal ideation of mianserin, maprotiline and amitriptyline.
TL;DR: A highly significant difference was observed in favour of mianserin against maprotiline on both items of suicl Thoughts'andsuiclthoughts′andpessimistic thoughts' on the MADS and the suicidal item on the HRS showed a similar tendency which did not reach significance.
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