15 Papers
129 Citations
Bo Richter is an academic researcher from National Research Foundation of South Africa. The author has contributed to research in topics: Enantioselective synthesis & Organocatalysis. The author has an hindex of 7, co-authored 15 publications.
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Papers
Organocatalytic asymmetric synthesis of functionalized 3,4-dihydropyran derivatives.
TL;DR: The screening of different secondary amines as catalysts in toluene revealed that (S)-2-[bis(3,5-bistrifluoromethylphenyl)trimethyl-silanyloxymethyl]pyrrolidine (4a) gave full conversion affording the 3,4-dihydropyran 3a with 72% ee (Table 1, entry 1).
Bisoxazoline-Lewis acid-catalyzed direct-electron demand oxo-hetero-Diels-Alder reactions of N-oxy-pyridine aldehyde and ketone derivatives.
TL;DR: The catalytic and asymmetric oxo-hetero-Diels-Alder reaction of electron-rich dienes with N-oxy-pyridine-2-carbaldehyde and ketone derivatives, catalyzed by chiral copper(II)-bisoxazoline complexes, gives optically active six-membered oxygen heterocycles in moderate to good yields and with excellent enantioselectivities.
Enantioselective Organocatalytic Approach to α-Methylene-δ-lactones and δ-Lactams
TL;DR: This methodology utilizes the Michael addition of unmodified aldehydes to ethyl 2-(diethoxyphosphoryl)acrylate as the key step affording highly enantiomerically enriched adducts, which can be transformed into the target compounds maintaining the high stereoselectivity achieved in the first step.