Bo Ding
Yale University
8 Papers
289 Citations
Bo Ding is an academic researcher from Yale University. The author has contributed to research in topics: Transcription factor & Cellular differentiation. The author has an hindex of 8, co-authored 8 publications.
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Papers
The MyoD-inducible p204 protein overcomes the inhibition of myoblast differentiation by Id proteins
TL;DR: It is reported that p204 is required for the differentiation of C2C12 myoblasts and proposed that it enables the differentiation, at least in part, by overcoming the inhibition of the activities of the MyoD and E47 proteins by the Id proteins: Id1, Id2, and Id3.
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The interferon-inducible p204 protein acts as a transcriptional coactivator of Cbfa1 and enhances osteoblast differentiation.
Chuan-ju Liu,Eric Y. Chang,Jin Yu,Cathy S. Carlson,Lisa Prazak,Xiu Ping Yu,Bo Ding,Peter Lengyel,Paul E. Di Cesare +8 more
TL;DR: In this article, an interferon-inducible protein, p204, was shown to inhibit cell proliferation and promote the differentiation of myoblasts to myotubes, is a novel regulator in the course of osteogenesis.
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The Retinoblastoma Protein Is an Essential Mediator of Osteogenesis That Links the p204 Protein to the Cbfa1 Transcription Factor Thereby Increasing Its Activity
Yi Luan,Yi Luan,Xiuping Yu,Ke Xu,Bo Ding,Jin Yu,Yan Huang,Ning Yang,Peter Lengyel,Paul E. Di Cesare,Chuan-ju Liu,Chuan-ju Liu +11 more
TL;DR: It is established that suppression of p204 expression by an adenovirus construct encoding p204 antisense RNA inhibited osteoblast-specific gene activation by Cbfa1 in an osteogenesis assay involving the pluripotent C2C12 mesenchymal cell line.
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The Interferon-inducible p202a Protein Modulates NF-κB Activity by Inhibiting the Binding to DNA of p50/p65 Heterodimers and p65 Homodimers While Enhancing the Binding of p50 Homodimers
TL;DR: In this article, the authors demonstrate that p202a can inhibit in vitro and in vivo the binding to DNA of p65 homodimers and p50/65 heterodimmers, whereas it increases the binding of p50 hommodimers.
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p204 Protein Overcomes the Inhibition of the Differentiation of P19 Murine Embryonal Carcinoma Cells to Beating Cardiac Myocytes by Id Proteins
TL;DR: It is reported that endogenous or ectopic inhibitor of differentiation (Id) proteins inhibited the differentiation of P19 cells to myocytes, and p204 overcame this inhibition by Id proteins in consequence of binding and sequestering Id proteins, and accelerating their ubiquitination and degradation by proteasomes.
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