Bo Blomgren
AstraZeneca
18 Papers
205 Citations
Bo Blomgren is an academic researcher from AstraZeneca. The author has contributed to research in topics: Vascular endothelial growth factor & Tesaglitazar. The author has an hindex of 13, co-authored 17 publications. Previous affiliations of Bo Blomgren include Uppsala University.
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Papers
Increased blood flow and erythema in the posterior vestibular mucosa in vulvar vestibulitis
TL;DR: Women with vestibulitis have an increased superficial blood flow and erythema in the posterior parts of the vestibular mucosa, most probably caused by a neurogenic vasodilatation, which contributes to, but does not fully explain the ery thema.
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Increasing exposure levels cause an abrupt change in the absorption and metabolism of acutely inhaled benzo(a)pyrene in the isolated, ventilated, and perfused lung of the rat.
TL;DR: Results show that the absorption and metabolism of inhaled BaP in the lungs was highly dose dependent, and may explain the well-known difficulties of inducing lung cancer in laboratory animals with inhalants containing carcinogenic PAHs.
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Teratogenicity by the hERG potassium channel blocking drug almokalant: use of hypoxia marker gives evidence for a hypoxia-related mechanism mediated via embryonic arrhythmia.
TL;DR: It is shown that the potent IKr-blocking drug, almokalant, causes severe embryonic hypoxia and arrhythmia at stages (GDs 11 and 13) when developmental toxicity could be induced and IKR is functional and does not cause Hypoxia or affect heart rhythm at a developmental stage when IKkr is suppressed (GD 16) and potent Ikr blockers do not induce developmental toxicity.
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Wall discontinuities and increased expression of vascular endothelial growth factor-A and vascular endothelial growth factor receptors 1 and 2 in endometrial blood vessels of women with menorrhagia.
Miriam Mints,Kjell Hultenby,Eva Zetterberg,Bo Blomgren,Christian Falconer,Rick A. Rogers,Jan Palmblad +6 more
TL;DR: Endometrial blood vessels possess a discrete morphology that is characterized by endothelial gaps, and these gaps are more pronounced in women with IM, and are related to overexpression of VEGF-A and V EGF receptor 1, and might contribute to IM, e.g., by destablizing vessels.
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