Birgit Koschorz
Max Planck Society
9 Papers
7 Citations
Birgit Koschorz is an academic researcher from Max Planck Society. The author has contributed to research in topics: Heterochromatin & Embryonic stem cell. The author has an hindex of 6, co-authored 9 publications.
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Papers
Oct4 is required for primordial germ cell survival
James Kehler,E. N. Tolkunova,Birgit Koschorz,Maurizio Pesce,Luca Gentile,Michele Boiani,Hilda Lomelí,Hilda Lomelí,Andras Nagy,K. John McLaughlin,Hans R. Schöler,Hans R. Schöler,Alexey Tomilin,Alexey Tomilin +13 more
TL;DR: A previously unknown function of Oct4 in maintaining viability of mammalian germline is suggested using the conditional Cre/loxP gene targeting strategy to assess Oct4 function in primordial germ cells (PGCs).
Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation
Oscar Velazquez Camacho,Oscar Velazquez Camacho,Carmen Galán,Kalina Swist-Rosowska,Kalina Swist-Rosowska,Reagan W. Ching,Michael Gamalinda,Fethullah Karabiber,Inti A. De La Rosa-Velázquez,Bettina Engist,Birgit Koschorz,Nicholas Shukeir,Megumi Onishi-Seebacher,Suzanne van de Nobelen,Thomas Jenuwein +14 more
TL;DR: An RNA-mediated mechanism for the stable chromatin interaction of the Suv39h KMT is revealed and a function for major satellite non-coding RNA in the organization of an RNA-nucleosome scaffold as the underlying structure of mouse heterochromatin is suggested.
The Epithelial Cell Adhesion Molecule EpCAM Is Required for Epithelial Morphogenesis and Integrity during Zebrafish Epiboly and Skin Development
Krasimir Slanchev,Thomas J. Carney,Marc P. Stemmler,Birgit Koschorz,Adam Amsterdam,Heinz Schwarz,Matthias Hammerschmidt,Matthias Hammerschmidt +7 more
TL;DR: The authors' data suggest that EpCAM acts as a partner of E-cadherin to control adhesiveness and integrity as well as plasticity and morphogenesis within simple epithelia.
147
Foxd3 controls heterochromatin-mediated repression of repeat elements and 2-cell state transcription.
Deepika Puri,Deepika Puri,Birgit Koschorz,Bettina Engist,Megumi Onishi-Seebacher,Devon Ryan,Mamilla Soujanya,Thomas Montavon +7 more
TL;DR: In this article, the forkhead domain transcription factor FOXD3 was identified as a regulator of major satellite repeats and MERVL transcription in mouse embryonic stem cells, leading to the derepression of MERVL and major satellite repeat as well as a subset of genes expressed in the 2-cell state.
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Patent
Nucleic acids involved in the responder phenotype and applications thereof
Bernhard Herrmann,Birgit Koschorz,Andreas Kispert +2 more
- 18 Nov 1998
TL;DR: In this article, the authors have proposed a method to encode expression products involved in the Responder function, which contributes to the phenomenon of transmission ratio distortion, and also relates to regulatory regions of the genes corresponding to said nucleic acid molecules.
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