Birgit Heller-Stilb
University of Düsseldorf
12 Papers
181 Citations
Birgit Heller-Stilb is an academic researcher from University of Düsseldorf. The author has contributed to research in topics: Taurine & Retinal degeneration. The author has an hindex of 12, co-authored 12 publications.
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Papers
Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice
Birgit Heller-Stilb,Claudia van Roeyen,Kristina Rascher,Hans-Georg Hartwig,Andrea Huth,Mathias W. Seeliger,Ulrich Warskulat,Dieter Häussinger +7 more
TL;DR: The retinal involvement identifies the taurine transporter as an important factor for the development and maintenance of normal retinal functions and morphology.
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Taurine transporter knockout depletes muscle taurine levels and results in severe skeletal muscle impairment but leaves cardiac function uncompromised
Ulrich Warskulat,Ulrich Flögel,Christoph Jacoby,Hans-Georg Hartwig,Michael Thewissen,Marc W. Merx,Andrej Molojavyi,Birgit Heller-Stilb,Jürgen Prof. Dr. med. Schrader,Dieter Häussinger +9 more
TL;DR: Taurine transport is identified as a crucial factor for the maintenance of skeletal muscle function and total exercise capacity, while cardiac muscle apparently can compensate for the loss of taurine.
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Blunted Apoptosis of Erythrocytes from Taurine Transporter Deficient Mice
Philipp A. Lang,Ulrich Warskulat,Birgit Heller-Stilb,Dan Y Huang,Almut Grenz,Svetlana Myssina,Michael Duszenko,Florian Lang,Dieter Häussinger,Volker Vallon,Thomas Wieder +10 more
TL;DR: A decreased sensitivity of mature erythrocytes from taut-/- mice to osmotic shock and oxidative stress is pointed to, rendering them more resistant to apoptosis.
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Taurine-induced long-lasting enhancement of synaptic transmission in mice: role of transporters.
Olga A. Sergeeva,A. N. Chepkova,N. Doreulee,Krister S. Eriksson,W. Poelchen,Irmhild Mönnighoff,Birgit Heller-Stilb,U. Warskulat,D. Häussinger,Helmut L. Haas +9 more
TL;DR: Taurine transporter-deficient mice displayed very low taurine levels in both structures and a low ability to develop LLETAU in the striatum, but not in the hippocampus, which may reflect the different vulnerabilities of these brain regions under pathological conditions that are accompanied by osmotic changes such as hepatic encephalopathy.
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Taurine deficiency and apoptosis: findings from the taurine transporter knockout mouse.
Ulrich Warskulat,Elena Borsch,Roland Reinehr,Birgit Heller-Stilb,Christian Roth,Martin Witt,Dieter Häussinger +6 more
TL;DR: Taut-/- and taut+/- mice develop moderate unspecific hepatitis and liver fibrosis beyond 1 year of age where hepatocyte apoptosis and activation of the CD95 system are pronounced.
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