The prevalence of allergic rhinitis has exhibited an upward trend, and diabetes is a common endocrine metabolic disorder. Treatment of allergic rhinitis complicated with diabetes has been marginally explored. This study aimed to observe the effect of rupatadine fumarate combined with acupoint application in the treatment of allergic rhinitis complicated with diabetes and its effect on serum IgE levels. Totally 80 patients with allergic rhinitis complicated with diabetes admitted to our hospital from December 2019 to December 2020 were recruited and assigned to receive either rupatadine fumarate (control group) or rupatadine fumarate plus acupoint application (research group). The clinical observation indexes of the two groups of patients before and after treatment were analyzed, and the clinical efficacy of the two groups was evaluated. Rupatadine fumarate plus acupoint application was associated with a significantly higher efficacy (23 cases of markedly effective, 14 cases of effective, and 3 cases of ineffective) versus rupatadine fumarate alone (14 cases of markedly effective, 16 cases of effective, and 10 cases of ineffective) (χ2 = 4.501, p = 0.034). The immunoglobulin E (IgE) and nasal mucosal eosinophils (EOS) levels of the two groups of patients after treatment decreased significantly, and the research group had lower results (p < 0.05). Patients in the research group showed significantly lower syndrome scores than those in the control group (p < 0.05). Rupatadine fumarate plus acupoint application resulted in significantly lower physical sign scores and interleukin-4 (IL-4) levels and higher levels of interferon-gamma (INF-γ) versus rupatadine fumarate alone (p < 0.05). The two groups showed a similar incidence of adverse events (p > 0.05). Rupatadine fumarate plus acupoint application may offer a viable alternative for the treatment of allergic rhinitis as it alleviates the clinical symptoms, improves the treatment efficiency, and enhances the anti-allergic effect of the drug, with a high safety profile.

/pdf/efficacy-and-safety-of-rupatadine-fumarate-combined-with-3tw584cg.pdf

Efficacy and Safety of Rupatadine Fumarate Combined with Acupoint Application in Allergic Rhinitis Complicated with Diabetes

The human face provides countless pieces of information, not least through the display of emotions, driving intensified research interest. Common research methods, such as self-reports, often neglect the subtlety of unconscious emotional responses or risk distortion due to subjective evaluations. Although emotions can occur unconsciously, they sometimes trigger the smallest physiological changes in terms of muscle movements in the face. Manually associating specific emotions with such subtle changes proves to be both time-consuming and intricate. Facereader software, a tool that evaluates video recordings to categorize facial expressions based on muscle movements, including basic emotions, receives more attention, with Noldus' FaceReader software being a prominent example. Nevertheless, a comprehensive pre-purchase guide detailing potential use cases and operational prerequisites is conspicuously lacking, and insights into processing generated data outputs remain confined. Addressing this gap, this paper contributes preliminarily to creating an overview of the use and handling of Noldus FaceReader in different research areas so far. Our findings illuminate pivotal factors for experimental scenario decision-making, offering valuable guidance for methodological considerations involving FaceReader. Consequently, a proposed pioneering guideline aims at standardizing FaceReader utilization, fostering accurate data management, and nuanced result interpretation. 

I can see how you feel—Methodological considerations and handling of Noldus's FaceReader software for emotion measurement

The effect of acupoint herbal patching on the quality of life of patients recovering from COVID-19: A protocol for systematic review and meta analysis.

Objectives: This study has as main objective to identify through quantitative and descriptive survey which are the most sold herbal medicines used for the treatment of constipation marketed by a drugstore in the city of Manaus. Methods: list which herbal medicines for constipation were sold in August 2019 to August 2020; present the types of herbal medicines that act on constipation; list the medicines that were sold for constipation and score the results if used rationally. This work is an exploratory and descriptive research conducted in a drugstore located in the city of Manaus, Amazonas. Results: the best selling herbal medicines for constipation the Naturetti® as 40% of herbal medicines for constipation, soon after Metamucil (35%), Tamarine (13%) and Olina Essence of Life (12%), between August 2019 to August 2020. Conclusion: irrational use of herbal medicines cause adverse side effects, however with proper dosage the results are positive.

Medicamentos fitoterápicos utilizados para constipação intestinal comercializados em uma drogaria da cidade de Manaus - AM

Abstract In order to explore a new model of talent training that integrates the cultivation of Chinese medical thinking and training, and to further standardize the work of the outpatient staff. This paper analyzes in detail the clinical thinking skills of TCM and divides them into 3 parts, namely theory, operation and thinking skills. Quantification of clinical thinking skills of TCM outpatient clinic staff by MEA algorithm. From the perspective of TCM thinking cultivation, a three-tier B/S architecture was used to design a standardized training system for TCM outpatient clinics. The results of the experiment showed that without any training, Nurse Wang’s scores on the written, operational and thinking skills exams remained the same. After routine TCM thinking development, Nurse Wu’s TCM written, operational and thinking skills scores improved by 3.15, 3.44 and 4.32 points, respectively. The improvement in performance after training was small and P > 0.05. Nurse Qian improved her TCM written, operational, and thinking skills scores by 6.44, 7.56, and 10.44 points, respectively, through the outpatient standardized training system, with the highest scores and P < 0.05. This verifies that the use of TCM outpatient standardized training system can solve the problems of insufficient TCM thinking cultivation and low TCM theoretical operation level, and provide platform support for the new model of high-level TCM clinical talent training reform.

Construction and practice of a standardized training system for outpatient clinics based on the cultivation of TCM thinking

The effectiveness of acupoint application of traditional Chinese medicine in treating primary dysmenorrhea: A protocol for meta-analysis and data mining.

The effectiveness of acupoint herbal patching for functional constipation: Protocol for a meta-analysis and data mining.

Background Sleep deprivation (SD) among young adults is a major public health concern. In humans, it has adverse effects on mood and results in serious health problems. Faced with SD, persons may take precautionary measures to try and reduce their risk. The aim of this study is to evaluate the efficacy and safety of electroacupuncture (EA) for the prevention of negative moods after SD. In addition, we will do a comparison of the effects of EA on mood after SD at different time points. Methods This randomized controlled trial (RCT) will be performed at the First Affiliated Hospital of Changchun University of Chinese Medicine in China. The Standards for Reporting Interventions in Clinical Trials of Acupuncture 2010 will be strictly adhered to. Forty-two healthy male volunteers will be distributed into acupoints electroacupuncture (AE) group, non-acupoints electroacupuncture (NAE) control group, or blank control group. This trial will comprise 1-week baseline (baseline sleep), 1-week preventative treatment, 30-h total sleep deprivation (TSD), and 24-h after waking follow-up period. Participants in the AE group and the NAE control group during the preventative treatment period will be administered with EA treatment once daily for 1 week. Participants in the blank control group will not be administered with any treatment. The primary outcome will be the Profile of Mood States (POMS) Scale. Secondary outcome measures will include changes in the Noldus FaceReader (a tool for automatic analysis of facial expressions) and Positive and Negative Affect Schedule (PANAS) Scale. Total sleep deprivation will be 30 h. During the 30-h TSD period, participants will be subjected to 11 sessions of assessment. Adverse events will be recorded. Discussion This study is designed to evaluate the efficacy and safety of EA for the prevention of negative moods after SD. The results of this trial will allow us to compare the effects of EA on mood after SD at different time points. Moreover, the findings from this trial will be published in peer-reviewed journals. Trial registration Chinese Clinical Trial Registry Chi2000039713 . Registered on 06 November 2020.

/pdf/efficacy-and-safety-of-electroacupuncture-treatment-in-the-33b1rgu0p6.pdf

Efficacy and safety of electroacupuncture treatment in the prevention of negative moods in healthy young men after 30 h of total sleep deprivation: study protocol for a single-center, single-blind, parallel-arm, randomized clinical trial.

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The effectiveness of acupoint application of traditional Chinese medicine in treating primary dysmenorrhea: A protocol for meta-analysis and data mining.

The effectiveness of acupoint herbal patching for functional constipation: Protocol for a meta-analysis and data mining.

Efficacy and safety of electroacupuncture treatment in the prevention of negative moods in healthy young men after 30 h of total sleep deprivation: study protocol for a single-center, single-blind, parallel-arm, randomized clinical trial.