Bing-Hua Jiang
Zhengzhou University
234 Papers
1.2K Citations
Bing-Hua Jiang is an academic researcher from Zhengzhou University. The author has contributed to research in topics: Protein kinase B & Biology. The author has an hindex of 76, co-authored 211 publications. Previous affiliations of Bing-Hua Jiang include Oregon Health & Science University & University of Iowa.
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Papers
Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer.
Cheng-Fei Jiang,Cheng-Fei Jiang,Zhumei Shi,Dong-Mei Li,Ying-Chen Qian,Yi Ren,Xiao-Ming Bai,Yun-Xia Xie,Lin Wang,Xin Ge,Wei-Tao Liu,Linlin Zhen,Ling-Zhi Liu,Bing-Hua Jiang,Bing-Hua Jiang,Bing-Hua Jiang +15 more
TL;DR: The identification of estrogen/miR-196a/SPRED1 cascade will shed light on new molecular mechanism of estrogen signaling in BC development and therapy and help clarify the mechanism and functional linkage between estrogen and miRNAs.
Cadmium Increases HIF-1 and VEGF Expression through ROS, ERK, and AKT Signaling Pathways and Induces Malignant Transformation of Human Bronchial Epithelial Cells
Yi Jing,Ling-Zhi Liu,Yue Jiang,Yingxue Zhu,Nancy Lan Guo,John B. Barnett,Yon Rojanasakul,Faton Agani,Bing-Hua Jiang +8 more
TL;DR: The results of this study provide explanation for the role and molecular mechanisms of cadmium in promoting angiogenesis in lung epithelial cells and malignant transformation and will be helpful for improved occupational protection, prevention, as well as chemotherapy of human lung cancers caused by heavy metal Cadmium.
Metallic nickel nano- and fine particles induce JB6 cell apoptosis through a caspase-8/AIF mediated cytochrome c-independent pathway
Jinshun Zhao,Linda Bowman,Xingdong Zhang,Xianglin Shi,Bing-Hua Jiang,Vincent Castranova,Min Ding +6 more
TL;DR: Investigating metallic nickel nano- and fine particle-induced apoptosis and the signal pathways involved in this process in JB6 cells found that metallic nickel nanoparticles exhibited higher cytotoxicity than fine particles.
Makorin-2 Is a Neurogenesis Inhibitor Downstream of Phosphatidylinositol 3-Kinase/Akt (PI3K/Akt) Signal
Pai Hao Yang,Pai Hao Yang,Pai Hao Yang,William K.C. Cheung,Ying Peng,Ming-Liang He,Guo Qing Wu,Guo Qing Wu,Dan Xie,Bing-Hua Jiang,Qiu Hua Huang,Zhu Chen,Marie C.M. Lin,Hsiang-Fu Kung +13 more
TL;DR: The cloned Xenopus makorin-2 was cloned and the important role of mkrn2 as a new player in PI3K/Akt-mediated neurogenesis during Xenopus embryonic development was revealed for the first time.
Cross-talk between Epidermal Growth Factor Receptor and Hypoxia-inducible Factor-1α Signal Pathways Increases Resistance to Apoptosis by Up-regulating Survivin Gene Expression
TL;DR: The results show that normoxic breast cancer cells utilize cross-talk between EGFR signals and Hif-1α to up-regulate the anti-apoptotic survivin gene, providing a strong rationale for the targeting of HIF-1 α as a therapeutic approach for both hypoxic and normoxic tumor cells.