13 Papers
43 Citations
Bin Zhu is an academic researcher from Chinese Ministry of Education. The author has contributed to research in topics: Nasopharyngeal carcinoma & Regulation of gene expression. The author has an hindex of 10, co-authored 13 publications.
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Papers
Over-expression of BCAT1, a c-Myc target gene, induces cell proliferation, migration and invasion in nasopharyngeal carcinoma
Wen Zhou,Xiangling Feng,Caiping Ren,Xingjun Jiang,Weidong Liu,Wei Huang,Zhihong Liu,Zan Li,Liang Zeng,Lei Wang,Bin Zhu,Jia Shi,Jie Liu,Chang Zhang,Yanyu Liu,Kaitai Yao,Kaitai Yao +16 more
TL;DR: This study indicates that gene amplification and c-Myc up-regulation are responsible for BCAT1 overeexpression in primary NPC, and overexpression of BCAT2 induces cell proliferation, migration and invasion, and suggests thatBCAT1 may be a novel molecular target for the diagnosis and treatment of NPC.
Roles of PTBP1 in alternative splicing, glycolysis, and oncogensis
Wei Zhu,Bo-lun Zhou,Li-juan Rong,Li Ye,Hong-juan Xu,Yao Zhou,Xue-jun Yan,Weidong Liu,Bin Zhu,Lei Wang,Xing-jun Jiang,Caiping Ren +11 more
TL;DR: The role of PTBP1 in cancer has become a popular research topic in recent years, and this research has contributed greatly to the formulation of a useful therapeutic strategy for cancer.
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells
Wei Jia,Xingjun Jiang,Weidong Liu,Lei Wang,Bin Zhu,Hecheng Zhu,Xingdong Liu,Meizuo Zhong,Dan Xie,Wei Huang,Wenting Jia,Shasha Li,Xuxu Liu,Xiang Zuo,Damei Cheng,Jianwu Dai,Caiping Ren +16 more
TL;DR: The results of the study suggested that the 3D collagen scaffold enhanced the malignancy of glioma cells and may be a promising in vitro platform for investigations ofglioma.
Underlying mechanisms for LTF inactivation and its functional analysis in nasopharyngeal carcinoma cell lines
Hejun Zhang,Xiangling Feng,Weidong Liu,Xingjun Jiang,Wenjiao Shan,Chengan Huang,Hongmei Yi,Bin Zhu,Wen Zhou,Lei Wang,Chunmei Liu,Lihua Zhang,Wenting Jia,Wei Huang,Guifei Li,Jia Shi,Siyi Wanggou,Kaitai Yao,Kaitai Yao,Caiping Ren,Caiping Ren +20 more
TL;DR: The data indicate LTF may participate in NPC carcinogenesis as a negative effector, that is, a tumor suppressor gene.
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Inhibition of store‑operated Ca2+ entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate
Wei Huang,Caiping Ren,Guoling Huang,Jie Liu,Weidong Liu,Lei Wang,Bin Zhu,Xiangling Feng,Jia Shi,Jinlong Li,Xiaomeng Xia,Wei Jia,Jiawen Chen,Yuxiang Chen,Xingjun Jiang +14 more
TL;DR: It is revealed that enhanced SOCE and activated mitochondrial apoptosis axis may account for the mechanisms of cytotoxicity of NaBu in NPC cells, and that NaBu serves as a promising chemotherapeutic agent in NPC therapy.