24 Papers
607 Citations
Bin Ye is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Ovarian cancer & Cancer. The author has an hindex of 16, co-authored 23 publications. Previous affiliations of Bin Ye include Harvard University.
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Papers
•Journal Article
Haptoglobin-α subunit as potential serum biomarker in ovarian cancer: Identification and characterization using proteomic profiling and mass spectrometry
Bin Ye,Daniel W. Cramer,Steven J. Skates,Steven P. Gygi,Vanessa Pratomo,Lanfei Fu,Nora Horick,Larry J. Licklider,John O. Schorge,Ross S. Berkowitz,Samuel C. Mok +10 more
TL;DR: Haptoglobin-derived α subunit is a potential marker for ovarian cancer that is complementary to CA125 and confirmation of protein identity with specific antibodies is crucial for clinical application and functional studies.
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Integration of cell phone imaging with microchip ELISA to detect ovarian cancer HE4 biomarker in urine at the point-of-care
ShuQi Wang,Xiaohu Zhao,Imran Khimji,Ragip Akbas,Weiliang Qiu,Dale Edwards,Daniel W. Cramer,Bin Ye,Utkan Demirci,Utkan Demirci +9 more
TL;DR: In this paper, a simple and inexpensive microchip ELISA-based detection module that employs a portable detection system, i.e., a cell phone/charge-coupled device (CCD) to quantify an ovarian cancer biomarker, HE4, in urine.
Proteomic-based discovery and characterization of glycosylated eosinophil-derived neurotoxin and COOH-terminal osteopontin fragments for ovarian cancer in urine.
Bin Ye,Steven J. Skates,Samuel C. Mok,Nora Horick,Helene F. Rosenberg,Allison F. Vitonis,Dale Edwards,Patrick M. Sluss,Won K. Han,Ross S. Berkowitz,Daniel W. Cramer +10 more
TL;DR: Urine with less complexity than serum and relatively high thermodynamic stability of peptides or metabolites is a promising study medium for discovery of the novel biomarkers which may present in many nonurinary tract neoplastic diseases.
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Blood and urine markers for ovarian cancer: a comprehensive review.
Kathryn L. Terry,Patrick M. Sluss,Steven J. Skates,Samuel C. Mok,Bin Ye,Allison F. Vitonis,Daniel W. Cramer +6 more
TL;DR: This work has shown clear trends in women’s ob-Gyn morbidity and mortality during the first trimester of pregnancy and these trends are continuing into the second half of the decade.
Use of a Combination of Approaches to Identify and Validate Relevant Tumor-Associated Antigens and Their Corresponding Autoantibodies in Ovarian Cancer Patients
Audrey Gagnon,Jae Hoon Kim,John O. Schorge,Bin Ye,Brian C.-S. Liu,Kathleen Hasselblatt,William R. Welch,Christina A. Bandera,Samuel C. Mok +8 more
TL;DR: The use of proteomics, immunology, and ELISA methods to identify relevant autoantibodies directed against the S100A7 protein in the plasma of ovarian cancer patients shows that this approach is a valuable tool to successfully identify autoantibia and tumor-associated antigens in cancer patients and that future research assessing their putative clinical usefulness would be worthwhile.
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