Bin Wei
Chinese Academy of Sciences
35 Papers
172 Citations
Bin Wei is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Biology & Cytotoxic T cell. The author has an hindex of 18, co-authored 30 publications. Previous affiliations of Bin Wei include Tongji University & Shanghai University.
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Papers
E-Cadherin-Mediated Cell–Cell Contact Is Critical for Induced Pluripotent Stem Cell Generation
Taotao Chen,Detian Yuan,Bin Wei,Jing Jiang,Jiuhong Kang,Jiuhong Kang,Kun Ling,Yijun Gu,Jinsong Li,Lei Xiao,Gang Pei,Gang Pei +11 more
TL;DR: The results highlight the critical role of E‐cadherin‐mediated cell–cell contact in reprogramming and suggest new routes for more efficient iPS cell generation.
252
Spleen mediates a distinct hematopoietic progenitor response supporting tumor-promoting myelopoiesis
Chong Wu,Huiheng Ning,Mingyu Liu,Jie Lin,Shufeng Luo,Wenjie Zhu,Jing Xu,Wen Chao Wu,Jing Liang,Chun Kui Shao,Jiaqi Ren,Bin Wei,Jun Cui,Minshan Chen,Limin Zheng +14 more
TL;DR: It is shown that the heightened splenic myelopoiesis in tumor-bearing hosts was not only characterized by the accumulation of myeloid precursors, but also associated with profound functional alterations of splenic early hematopoietic stem/progenitor cells (HSPCs) that were “primed” and committed to generating immunosuppressiveMyeloid cells.
Elucidation of the MD-2/TLR4 Interface Required for Signaling by Lipid IVa
Catherine M. Walsh,Monique Gangloff,Tom P. Monie,Tomoko Smyth,Bin Wei,Trevelyan J. McKinley,Duncan J. Maskell,Clare E. Bryant +7 more
TL;DR: A mechanism of signaling that involves crosslinking mediated by both MD-2-receptor and receptor-re receptor contacts in a model that shows striking similarities to the recently published structure of the ligand-bound TLR1/2 ectodomain heterodimer is suggested.
127
CTLA-4 up-regulation of lymphocyte function-associated antigen 1 adhesion and clustering as an alternate basis for coreceptor function
TL;DR: The surprising finding that CTLA-4 engagement by soluble antibody or CD80 potently up-regulates lymphocyte function-associated antigen 1 (LFA-1) adhesion to intercellular adhesion molecule-1 (ICAM- 1) and receptor clustering concurrent with IL-2 inhibition is reported.
125
STK4 regulates TLR pathways and protects against chronic inflammation–related hepatocellular carcinoma
Weiyun Li,Jun Xiao,Xin Zhou,Ming Xu,Chaobo Hu,Xiaoyan Xu,Yao Lu,Chang Liu,Shengjie Xue,Lei Nie,Haibin Zhang,Zhiqi Li,Yanbo Zhang,Fu Ji,Lijian Hui,Wufan Tao,Bin Wei,Hongyan Wang +17 more
TL;DR: It is demonstrated that the tumor suppressor serine/threonine-protein kinase 4 (STK4) differentially regulates TLR3/4/9-mediated inflammatory responses in macrophages and thereby is protective against chronic inflammation-associated HCC.