Bin Wang
Jilin University
7 Papers
1 Citations
Bin Wang is an academic researcher from Jilin University. The author has contributed to research in topics: Staphylococcus aureus & Lytic cycle. The author has an hindex of 5, co-authored 7 publications.
Chat about Author
Papers
Combination Therapy of LysGH15 and Apigenin as a New Strategy for Treating Pneumonia Caused by Staphylococcus aureus
Feifei Xia,Li Xin,Bin Wang,Pengjuan Gong,Feng Xiao,Mei Yang,Lei Zhang,Jun Song,Liyuan Hu,Mengjun Cheng,Changjiang Sun,Xin Feng,Liancheng Lei,Songying Ouyang,Zhi-Jie Liu,Xinwei Li,Jingmin Gu,Wenyu Han +17 more
TL;DR: The combination therapy of LysGH15 and apigenin exhibits therapeutic potential for treating pneumonia caused by MRSA and shows the best health status, the lowest ratio of wet tissue to dry tissue of the lungs, the smallest amount of total protein and cells in the lung, the fewest pathological manifestations, and the lowest cytokine level.
60
An Ointment Consisting of the Phage Lysin LysGH15 and Apigenin for Decolonization of Methicillin-Resistant Staphylococcus aureus from Skin Wounds
Mengjun Cheng,Lei Zhang,Hao Zhang,Xinwei Li,Yanmei Wang,Feifei Xia,Bin Wang,Ruopeng Cai,Zhimin Guo,Yufeng Zhang,Yalu Ji,Changjiang Sun,Xin Feng,Liancheng Lei,Yongjun Yang,Wenyu Han,Wenyu Han,Jingmin Gu +17 more
TL;DR: The potential efficacy of a combination of LysGH15 and api for use as a topical antimicrobial agent against S. aureus is demonstrated and the levels of pro-inflammatory cytokines are reduced and accelerated wound healing in the mouse model.
50
Therapeutic effect of the YH6 phage in a murine hemorrhagic pneumonia model.
Mei Yang,Chongtao Du,Pengjuan Gong,Feifei Xia,Changjiang Sun,Xin Feng,Liancheng Lei,Jun Song,Lei Zhang,Bin Wang,Feng Xiao,Xinwu Yan,Ziyin Cui,Xinwei Li,Jingmin Gu,Wenyu Han +15 more
TL;DR: In view of its protective efficacy in this murine hemorrhagic pneumonia model, YH6 may serve as an alternative treatment strategy for infections caused by multidrug-resistant P. aeruginosa.
37
Salmonella Typhimurium strain expressing OprF-OprI protects mice against fatal infection by Pseudomonas aeruginosa
Mingliang Zhang,Changjiang Sun,Jingmin Gu,Xinwu Yan,Bin Wang,Ziyin Cui,Xiaoyu Sun,Chunyu Tong,Xin Feng,Liancheng Lei,Wenyu Han +10 more
TL;DR: Results indicate that s.c. vaccination provides a better protective response against P. aeruginosa infection than do oral administration and the His‐F1I2 vaccine.
12
Patent
Genetically engineered lysin with function of killing staphylococcus, as well as preparation method and application thereof
Wenyu Han,Jingmin Gu,Yalu Ji,Zhimin Guo,Mengjun Cheng,Lei Zhang,Yufeng Zhang,Feifei Xia,Bin Wang,Xiao Feng +9 more
- 14 Jan 2020
TL;DR: In this paper, a genetically engineered lysin with a function of killing staphylococcus and a preparation method was revealed, and a bacteriophage Lysin LysGH15(+) was obtained.
1