Bin Ling
Anhui Medical University
5 Papers
19 Citations
Bin Ling is an academic researcher from Anhui Medical University. The author has contributed to research in topics: Cancer & Koilocyte. The author has an hindex of 4, co-authored 5 publications.
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Papers
Down-regulation of GRIM-19 expression is associated with hyperactivation of STAT3-induced gene expression and tumor growth in human cervical cancers.
Ying Zhou,Min Li,Ying Wei,Dingqing Feng,Cheng Peng,Haiyan Weng,Yang Ma,Liang Bao,Shreeram C. Nallar,Sudhakar Kalakonda,Weihua Xiao,Dhananjaya V. Kalvakolanu,Bin Ling +12 more
TL;DR: Using a surrogate model, restoration of GRIM-19 levels reestablishes the control over STAT3-dependent gene expression and tumor growth in vivo and identifies another major novel molecular pathway inactivated during the development of human cervical cancer.
Up-regulation of ITCH is associated with down-regulation of LATS1 during tumorigenesis and progression of cervical squamous cell carcinoma.
Ying Zhou,Feng Tao,Yong Cheng,Fei Xu,Fengqiu Yao,Dingqing Feng,Lin Miao,Weihua Xiao,Bin Ling +8 more
TL;DR: ITCH up-regulation and LATS1 down-regulation were closely associated with tumorigenesis and progression of SCC; therefore, inhibiting the expression of ITCH may serve as a novel therapeutic strategy for impeding the progression of precancerous neoplasm to SCC.
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In vivo activity of novel anti-ErbB2 antibody chA21 alone and with Paclitaxel or Trastuzumab in breast and ovarian cancer xenograft models
Guodong Shen,Huang Hui,Anli Zhang,Ting Zhao,Siyi Hu,Liansheng Cheng,Jing Liu,Weihua Xiao,Bin Ling,Qiang Wu,Lihua Song,Wei Wei +11 more
TL;DR: The study reveals that the effects by chA21 to cause an enhanced inhibition on cancer cell proliferation and angiogenesis was highly associated with the intrinsic ability of chA 21 to down-regulate ErbB2 receptor, inhibit downstream MAPK and PI3K-AKT signal transduction and activate natural killer cells.
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Reduced expression of ΔΝp63α in cervical squamous cell carcinoma
TL;DR: The decrease of p63α in cervical squamous cell cancer appears to be associated with the tumour progression, and ΔΝp63α may be a sensitive marker for cervicalSquamous cancer differentiation.
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Patent
Simple cell climbing film culture and experimental apparatus
Bin Ling,Ying Zhou,Ying Wei,Min Li,Dingqing Feng +4 more
- 31 Dec 2008
TL;DR: In this article, a simple cell climbing film culture and experimental apparatus consisting of a base with a rectangular groove for horizontally placing a glass slide, horizontal bayonets positioned above the rectangular groove and arranged in two side walls corresponding to the base, and atube body, wherein, a through hole is formed on a bottom plate of the base and in the center position corresponding to a sliding window, and a sealing ring is arranged at the bottom opening of the tube body.
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