Bin Guo
Chongqing Medical University
17 Papers
19 Citations
Bin Guo is an academic researcher from Chongqing Medical University. The author has contributed to research in topics: Biosensor & Chemistry. The author has an hindex of 8, co-authored 16 publications. Previous affiliations of Bin Guo include North Sichuan Medical College.
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Papers
Collapse of DNA Tetrahedron Nanostructure for “Off–On” Fluorescence Detection of DNA Methyltransferase Activity
Xiaoyan Zhou,Xiaoyan Zhou,Min Zhao,Xiaolei Duan,Bin Guo,Wei Cheng,Shijia Ding,Huangxian Ju,Huangxian Ju +8 more
TL;DR: A novel multifunctional nanostructure has been developed as an "off-on" fluorescent probe for detection of target methyltransferase by integrating the elements of DNA tetrahedron, target recognition, and dual-labeled reporter in the field of clinical diagnostics.
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An enzyme-free and label-free surface plasmon resonance biosensor for ultrasensitive detection of fusion gene based on DNA self-assembly hydrogel with streptavidin encapsulation
TL;DR: This proposed strategy presents a powerful platform for ultrasensitive detection of fusion gene and early diagnosis and monitoring of disease and shows excellent practical ability to identify the clinical PCR products of PML/RARα.
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Trimetallic hybrid nanodendrites and magnetic nanocomposites-based electrochemical immunosensor for ultrasensitive detection of serum human epididymis protein 4
TL;DR: A robust and ultrasensitive electrochemical immunosensor, based on AgPtCo NDs and magnetic nanocomposites (Fe3O4@SiO2@Au MNCs), was successfully developed to detect serum human epididymis protein 4 (HE4) as discussed by the authors.
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An Enzyme-Free “ON-OFF” Electrochemiluminescence Biosensor for Ultrasensitive Detection of PML/RARα based on Target-Switched DNA Nanotweezer
TL;DR: An enzyme-free "ON-OFF" electrochemiluminescence (ECL) biosensor for ultrasensitive detection of fusion gene PML/RARα is constructed based on a simple target-switched DNA nanotweezer as hemin concentration controller, which shows excellent specificity to the other subtypes of PML and RARα.
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An integrated electrochemical biosensor based on target-triggered strand displacement amplification and "four-way" DNA junction towards ultrasensitive detection of PIK3CA gene mutation.
TL;DR: This novel electrochemical biosensor was constructed for specific and ultrasensitive detection of PIK3CAH1047R gene mutation based on NsbI restriction enzyme-mediated strand displacement amplification (NsbI-SDA) and four-way DNA junction and could be used to analyze mutation gene spiked into human serum samples, indicating the potential application in genetic analysis and clinical disease diagnosis.
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