Bin Gu
Fudan University
12 Papers
23 Citations
Bin Gu is an academic researcher from Fudan University. The author has contributed to research in topics: Cancer & Apoptosis. The author has an hindex of 7, co-authored 12 publications.
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Papers
The prognostic value of C-reactive protein in renal cell carcinoma: a systematic review and meta-analysis.
TL;DR: Elevated CRP level in a patient with RCC is associated with poorer prognosis, and it could serve as a useful biomarker for clinical prediction.
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EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression.
TL;DR: This is the first report showing that EGCG is likely to be an effective agent for renal cell carcinoma through TFPI-2 overexpression, and using MTT and flow cytometry, it is demonstrated that E GCG can inhibit growth and induces apoptosis in renal cancer cell line 786-0.
iTRAQ-based quantitative proteomic analysis reveals potential early diagnostic markers of clear-cell Renal cell carcinoma.
Limin Zhang,Haowen Jiang,Gang Xu,Nan Chu,Nan Chu,Ningxing Xu,Hui Wen,Bin Gu,Jun Liu,Shanghua Mao,Rong Na,Yan Jing,Qiang Ding,Yuan-fang Zhang,Ling Wang,Ling Wang +15 more
TL;DR: There were 27 differentially expressed proteins in early-stage RCC identified by iTRAQ; among them, the expression of C1QC, C1QB, S 100A8, S100A9, ceruplasmin, and lumican were associated with the tumor stage and/or grade.
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Proteins S100A8 and S100A9 are potential biomarkers for renal cell carcinoma in the early stages: Results from a proteomic study integrated with bioinformatics analysis
Limin Zhang,Haowen Jiang,Gang Xu,Hui Wen,Bin Gu,Jun Liu,Shanghua Mao,Rong Na,Yan Jing,Qiang Ding,Yuan-fang Zhang +10 more
TL;DR: In this article, the two members of the EF-hand Ca2+ binding protein S100 family, S100A8 and S 100A9, were found to be upregulated in patients with RCC compared with the other three groups, which was consistent with the result of the upregulated expression of mRNA levels in RCC tissue.
•Journal Article
TFPI-2 expression is decreased in bladder cancer and is related to apoptosis.
TL;DR: TFPI-2 expression was decreased with progression in tumor grade and stage and was correlated to decreased apoptosis, indicating that TFPi-2 could be a marker of bladder cancer and enhancement of TFPI -2 could combat bladder cancer.
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