Billy Bourke
University College Dublin
110 Papers
713 Citations
Billy Bourke is an academic researcher from University College Dublin. The author has contributed to research in topics: Campylobacter jejuni & Medicine. The author has an hindex of 37, co-authored 105 publications. Previous affiliations of Billy Bourke include Our Lady's Children's Hospital & Boston Children's Hospital.
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Papers
Age-specific incidence of Helicobacter pylori.
TL;DR: Children who become infected with Helicobacter pylori are infected at a very young age, and the risk of infection declines rapidly after 5 years of age, which has important implications for studies on the mode of transmission of infection.
275
Differences in presentation and progression between severe FIC1 and BSEP deficiencies
Ludmila Pawlikowska,Sandra Strautnieks,Irena Jankowska,Piotr Czubkowski,Karan M. Emerick,Anthony Antoniou,Catherine Wanty,Björn Fischler,Emmanuel Jacquemin,Sami Wali,Samra Blanchard,Inge-Merete Nielsen,Billy Bourke,Shirley McQuaid,Florence Lacaille,J A Byrne,Albertien M. van Eerde,Kaija-Leena Kolho,Leo W. J. Klomp,Roderick H. J. Houwen,Peter Bacchetti,Steven J. Lobritto,Vera Hupertz,Patricia McClean,Giorgina Mieli-Vergani,Benjamin L. Shneider,Antal Nemeth,Etienne Sokal,Nelson B. Freimer,A.S. Knisely,Philip J. Rosenthal,Peter F. Whitington,Joanna Pawłowska,Richard J. Thompson,Laura N. Bull +34 more
TL;DR: Clinical and laboratory features of disease in patients diagnosed with PFIC, who carried mutations in ATP8B1 (FIC1 deficiency) or ABCB11 (BSEP deficiency) were evaluated to identify features that distinguish presentation and course of these two disorders, thus facilitating diagnosis and elucidating the differing consequences of ATP 8B1 and ABCB 11 mutations.
190
Focally enhanced gastritis in children with Crohn’s disease and ulcerative colitis
F Sharif,Michael McDermott,M Dillon,Brendan Drumm,Marion Rowland,C Imrie,S Kelleher,S. Harty,Billy Bourke +8 more
TL;DR: The presence of FEG suggests underlying IBD, which is particularly common in children with Crohn's disease, but it does not reliably differentiate between Crohn’s disease and ulcerative colitis.
129
Defects in NADPH Oxidase Genes NOX1 and DUOX2 in Very Early Onset Inflammatory Bowel Disease.
PK Hayes,Sandeep S. Dhillon,Kim O’Neill,Cornelia Thoeni,Ken Y. Hui,Abdul Elkadri,Conghui H. Guo,Lidija Kovačič,Gabriella Aviello,Luis Alvarez,Anne M. Griffiths,Scott B. Snapper,Steven R. Brant,James H. Doroshow,Mark S. Silverberg,Inga Peter,Dermot P.B. McGovern,Judy H. Cho,John H. Brumell,Holm H. Uhlig,Billy Bourke,Billy Bourke,Aleixo M. Muise,Ulla G. Knaus,Ulla G. Knaus +24 more
TL;DR: This study identifies the first inactivating missense variants in NOX1 and DUOX2 associated with VEOIBD, indicating defective ROS production from intestinal epithelial cells constitutes a risk factor for developing VEO IBD.
125
Enteric campylobacter: purging its secrets?
TL;DR: Understanding of the molecular and cellular pathogenesis of Campylobacter infection has lagged far behind that of other enteric pathogens, but recent completion of the genome sequence of Campyobacter jejuni promises to open up the research field with the prospect of developing novel therapeutic and preventive strategies.