Bidisha Pal
University of Massachusetts Amherst
19 Papers
4 Citations
Bidisha Pal is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Stem cell & Biology. The author has an hindex of 5, co-authored 9 publications. Previous affiliations of Bidisha Pal include University of Texas at Tyler & Indian Institute of Technology Guwahati.
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Papers
MYC Regulates the HIF2α Stemness Pathway via Nanog and Sox2 to Maintain Self-Renewal in Cancer Stem Cells versus Non-Stem Cancer Cells
Bikul Das,Bidisha Pal,Bidisha Pal,Bidisha Pal,Rashmi Bhuyan,Hong Li,Hong Li,Hong Li,Anupam Sarma,Anupam Sarma,Sukanya Gayan,Sukanya Gayan,Sukanya Gayan,Joyeeta Talukdar,Sorra Sandhya,Seema Bhuyan,Gayatri Gogoi,Gayatri Gogoi,Gayatri Gogoi,Arvin M. Gouw,Debabrat Baishya,Debabrat Baishya,Jason Gotlib,Amal C Kataki,Dean W. Felsher +24 more
TL;DR: It is reported that in a transgenic mouse model of MYC-induced T cell leukemia, MYC maintains self-renewal in Sca1+ CSCs versus Sca-1- non-CSCs and activates the HIF-2α stemness pathway.
Coronavirus Activates an Altruistic Stem Cell-Mediated Defense Mechanism that Reactivates Dormant Tuberculosis: Implications in Coronavirus Disease 2019 Pandemic.
Lekhika Pathak,Sukanya Gayan,Bidisha Pal,Joyeeta Talukdar,Seema Bhuyan,Sorra Sandhya,Herman Yeger,Debabrat Baishya,Bikul Das +8 more
TL;DR: In this article, a mesenchymal stem cell (MSC)-based altruistic defense against a mouse model of coronavirus, murine hepatitis virus-1 (MHV-1) infection of lung.
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Corona virus activates a stem cell mediated defense mechanism that accelerates activation of dormant tuberculosis: implications for the COVID-19 pandemic
Lekhika Pathak,Sukanya Gayan,Bidisha Pal,Bidisha Pal,Joyeeta Talukdar,Seema Bhuyan,Sorra Sandhya,Herman Yeger,Debabrat Baishya,Debabrat Baishya,Bikul Das,Bikul Das +11 more
TL;DR: The data suggest that MSCs exert an innate defense against MHV-1 by activating the ASC defense mechanism, which might be exploited by dormant Mtb to undergo reactivation, which may provide a novel anti-viral defense mechanism against novel corona virus SARS-Cov2.
Coronavirus activates a stem cell-mediated defense mechanism that reactivates dormant tuberculosis: implications in COVID-19 pandemic
Lekhika Pathak,Sukanya Gayan,Bidisha Pal,Bidisha Pal,Joyeeta Talukdar,Seema Bhuyan,Sorra Sandhya,Herman Yeger,Debabrat Baishya,Debabrat Baishya,Bikul Das,Bikul Das +11 more
TL;DR: In this article, a mouse model of mesenchymal stem cells (MSC) mediated Mycobacterium tuberculosis (Mtb) dormancy was used to develop a vaccine against COVID-19.
16
Targeting hypoxia-induced tumor stemness by activating pathogen-induced stem cell niche defense
Seema Bhuyan,Bidisha Pal,Lekhika Pathak,Partha jyoti Saikia,Shirsajit Mitra,Sukanya Gayan,Reza Bayat Mokhtari,Hong Li,Chilakamarti V. Ramana,Debabrat Baishya,Bikul Das +10 more
TL;DR: It is reported that post-hypoxia/reoxygenation SPm+/ABCG2+ CSCs exerts defense against pathogen invasion that involves bystander apoptosis of non-infected C SCs and serves a functional role as a tumor stemness defense (TSD) phenotype to protect TME against bacterial invasion.