Beverly Long

TL;DR: Among women with PMB mean ET is substantially higher in women with EC compared to those without EC, and an ET cutoff of ≥5 mm shows an acceptable tradeoff between sensitivity and specificity for diagnosis of EC.

TL;DR: BRCA1/2 and Lynch mutations were rare in this cohort of unselected patients with type I and II EC, including USC, but the presence of predisposition gene mutations in 4.2% of EC type I, 5.3% ofEC type II, and 6.7% of USC suggests that somatic mutation testing should be considered for all EC patients.

TL;DR: All patients diagnosed with EMPD should undergo cancer screening, and at minimum, evaluation should include age‐appropriate screening and the addition of urine cytology, mammography, and prostate‐specific antigen blood test, which may be of particular use.

TL;DR: The incidence of invasive vulvar EMPD has increased over time, and CSS is excellent for localized disease, but those with metastatic disease are in need of novel therapies, as well as site specific preventative health screens during recurrence surveillance.