14 Papers
89 Citations
Beth Baker is an academic researcher from The Research Institute at Nationwide Children's Hospital. The author has contributed to research in topics: Haemophilus ducreyi & Sexually transmitted disease. The author has an hindex of 11, co-authored 14 publications. Previous affiliations of Beth Baker include Nationwide Children's Hospital & Ohio State University.
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Papers
The PilA protein of non-typeable Haemophilus influenzae plays a role in biofilm formation, adherence to epithelial cells and colonization of the mammalian upper respiratory tract.
Joseph A. Jurcisek,James E. Bookwalter,Beth Baker,Soledad Fernandez,Laura A. Novotny,Robert S. Munson,Lauren O. Bakaletz +6 more
TL;DR: The data demonstrate that NTHI express PilA in vivo, and that PilA plays an important role in the pathogenesis of an upper respiratory tract infection induced by NTHi, both in vitro and in vivo.
153
Differential iron transport into phagosomes isolated from the RAW264.7 macrophage cell lines transfected with Nramp1Gly169 or Nramp1Asp169.
TL;DR: In this article, the transport of iron by RAW264.7 macrophage cell lines transfected with either Nramp1Gly169 (resistant) or NrAMP1ASp169 (susceptible) alleles was assessed and no difference between resistant and susceptible cells in the rate of Fe import or export when measured in intact cells.
116
The OxyR regulon in nontypeable Haemophilus influenzae.
Alistair Harrison,William C. Ray,Beth Baker,David W. Armbruster,Lauren O. Bakaletz,Robert S. Munson +5 more
TL;DR: Hydrogen peroxide induced the OxyR-independent upregulation of expression of the genes encoding components of multiple iron utilization systems, suggesting that careful balancing of levels of intracellular iron was important for minimizing the effects of oxidative stress during NTHi colonization and infection and that there are additional regulatory pathways involved in iron utilization.
55
Identification of genes involved in the expression of atypical lipooligosaccharide structures from a second class of Haemophilus ducreyi.
Deborah M. B. Post,Robert S. Munson,Beth Baker,Huachun Zhong,Joel A. Bozue,Bradford W. Gibson,Bradford W. Gibson +6 more
TL;DR: It is demonstrated that the product of one of the lbgAB genes encodes a galactosyltransferase, which can serve as one indicator of the classification of H. ducreyi strains.
30
HrrF is the Fur-regulated small RNA in nontypeable Haemophilus influenzae.
Estevan A. Santana,Alistair Harrison,Xinjun Zhang,Beth Baker,Beth Baker,Benjamin J. Kelly,Peter White,Yunlong Liu,Robert S. Munson,Robert S. Munson +9 more
TL;DR: HrrF, the first small RNA described in any Haemophilus species, was identified and showed that HrrF is maximally expressed when iron levels are low, and Fur was shown to bind upstream of the hrrF promoter.