Bertossi M
University of Foggia
23 Papers
123 Citations
Bertossi M is an academic researcher from University of Foggia. The author has contributed to research in topics: Blood–brain barrier & Human brain. The author has an hindex of 13, co-authored 23 publications.
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Papers
Expression of P-glycoprotein in human cerebral cortex microvessels.
Daniela Virgintino,David Robertson,Mariella Errede,Vincenzo Benagiano,Francesco Girolamo,Eugenio Maiorano,Luisa Roncali,Bertossi M +7 more
TL;DR: The results show that P-gp marks the microvessels of the cortex and that the transporter is localized in the luminal endothelial compartment, where it co-localizes with caveolin-1, leading to suggest that interactions between these molecules may occur at the BBB endothelia.
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Expression of caveolin-1 in human brain microvessels.
Daniela Virgintino,David Robertson,Mariella Errede,Vincenzo Benagiano,U Tauer,Luisa Roncali,Bertossi M +6 more
TL;DR: The demonstration of caveolin-1 in the cells of the brain microvessels suggests that caveolin -1 may be involved in blood-brain barrier functioning, and also supports co-ordinated activities between these cells.
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Astroglia-microvessel relationship in the developing human telencephalon
Daniela Virgintino,Eugenio Maiorano,Mariella Errede,Antonella Vimercati,Pantaleo Greco,L. Selvaggi,Luisa Roncali,Bertossi M +7 more
TL;DR: The observations taken as a whole, suggest that during the telencephalon morphogenesis the immature astroglia cells play a role in the early establishment of the distribution pattern of the neural microvessels and in their growth and maturation.
Effects of methylmercury on the microvasculature of the developing brain.
Bertossi M,Francesco Girolamo,Mariella Errede,Daniela Virgintino,G Elia,L. Ambrosi,Luisa Roncali +6 more
TL;DR: The hypothesis that MeHg-related neuronal sufferance may be secondary to astrocytic damage is supported and the developmental neurotoxicity of this compound could also be related toAstrocyte loss-dependent impairment of blood-brain barrier (BBB) differentiation.
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•Journal Article
Role of basic fibroblast growth factor in the formation of the capillary plexus in the chick embryo chorioallantoic membrane. An in situ hybridization, immunohistochemical and ultrastructural study.
Domenico Ribatti,Bertossi M,B Nico,Angelo Vacca,Roberto Ria,Alessandro Riva,Roncali L,Marco Presta +7 more
TL;DR: These findings strongly suggest that FGF2 regulates the development of the capillary plexus by two sequential steps: in an early paracrine phase, chorionic epithelial cells secrete FGF1, thus eliciting an angiogenic response in the undifferentiated mesodermal blood vessels, and in a later phase, the newly formed endothelial cells move through a permissive ECM and migrate beneath the chorion.
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