A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthetic valve assembly expands to an expanded position such that the valve and valve support expand within the deficient native valve, and the anchor engages the lumen wall.

Prosthetic Valve For Transluminal Delivery

A system for delivering and deploying a self-expandable heart valve to a site of implantation such as the aortic annulus includes a deployment mechanism that engages the valve and regulates the rate of expansion of both the proximal and distal ends thereof. The heart valve may be a rolled-type valve and the deployment mechanism may include a plurality of distal fingers and a plurality of proximal fingers that engage the outer layer of the heart valve. Controlled radial movement of the fingers regulates the unwinding of the rolled heart valve. The fingers may be removed prior to inflation of a balloon to fully expand the valve, or the fingers may be repositioned to the inside of the valve for this purpose. The deployment mechanism may include an umbrella structure that forces the rolled valve outward into its fully expanded configuration. Alternatively, a gear shaft that engages one or more gear tracks on the valve may be utilized to regulate expansion of the valve. A stabilization balloon may be used to axially and radially locate the deployment mechanism relative to the site of implantation. Methods of operation of the delivery and deployment mechanism include regulating the rate of self-expansion of the valve and forcing the valve outward into its fully expanded configuration utilizing the same or different means.

Methods and apparatuses for deploying minimally-invasive heart valves

The invention concerns an assembly comprising a valve prosthesis to be implanted and a support receiving said valve. The support comprises: at least a tubular portion made of a pliable material slightly stretchable in the circumferential direction; means for fixing said tubular portion to the wall of the corporeal duct; and a plurality of elongated reinforcing elements, arranged on the circumference of said tubular portion and linked to said tubular portion independently of one another; the valve is linked at least partly to said elongated reinforcing elements, in particular at the commissures of its leaflets, and said elongated reinforcing elements jointly form, in extended position, a structure having a predetermined diameter that ensures sufficient extension of said valve.

Assembly for setting a valve prosthesis in a corporeal duct

Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat.

Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures

An apparatus and method is provided for stenting bifurcated vessels. A proximal angled stent is configured for implanting in a side-branch vessel wherein the proximal angled stent has an angulated portion that corresponds to the angle formed by the intersection of the side-branch vessel and the main vessel so that all portions of the side-branch vessel at the bifurcation are covered by the proximal angled stent. A main-vessel stent is provided for implanting in the main vessel, wherein the main-vessel stent has an aperture or stent cell that aligns with the opening to the side-branch vessel to permit unobstructed blood flow between the main vessel and the side-branch vessel. Side-branch and main-vessel catheter assemblies are advanced over a pair of guide wires for delivering, appropriately orienting, and implanting the proximal angled stent and the apertured stent.

Stent and catheter assembly and method for treating bifurcations

The present invention is a device for delivering a self-expanding stent. The device has an inner shaft and an outer shaft moveable with respect to the inner shaft. The self expanding stent is received on the inner shaft adjacent its distal end. A tapered tip is located on the inner shaft distal end and it forms a smooth transition from the delivery device to the guide wire extending therethrough. A handle allows the practitioner to deploy the stent single handedly. The stent may have its segments in a first radial configuration for deliver of the stent or the stent may have a plurality of segments in a first radial configuration and a plurality of second segments in a second radial position.

Stent delivery system

A steerable delivery catheter includes an outer sheath with a housing disposed at a distal end thereof to define a chamber for a medical device, the chamber having an open distal end and a proximal inner shelf. An inner shaft is slidably disposed within the sheath and has an abutment attached to the distal end of the shaft, the abutment being slidably contained within the chamber. During navigation of the catheter, when the inner shaft is tensioned the abutment engages the shelf to apply a compressive force to the sheath to selectively deflect a distal region of the catheter. When the catheter has been navigated to the deployment site the sheath is withdrawn while the abutment maintains the medical device in place as it is deployed. A delivery method also is disclosed.

Steerable delivery catheter

A mandrel includes a mandrel body with a proximal major diameter barrel section, a diameter reducing/tapered portion and a distal minor diameter barrel section. The tapered portion connects the proximal major diameter barrel section and distal minor diameter barrel section. The proximal major diameter barrel section has a major diameter, the distal minor diameter barrel section has a minor diameter, the minor diameter less than the major diameter. The minor diameter is less than a diameter of an inner lumen of a coaxial catheter, and the major diameter exceeds the inner diameter of the outer lumen guidewire exit port of the coaxial catheter, and the tapered portion is sized to form a fluid seal the inner diameter of the outer lumen guidewire exit port. The distal minor diameter barrel section of the mandrel occupies and substantially seals and prevent flow through it to the catheter distal end guidewire entry port.

Catheter flushing mandrel

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Stent delivery system

Steerable delivery catheter

Catheter flushing mandrel