Bernd Radüchel
Schering AG
193 Papers
1.3K Citations
Bernd Radüchel is an academic researcher from Schering AG. The author has contributed to research in topics: Alkyl & Aryl. The author has an hindex of 21, co-authored 193 publications. Previous affiliations of Bernd Radüchel include University of Toledo Medical Center & Bayer.
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Papers
The Impact of Rigidity and Water Exchange on the Relaxivity of a Dendritic MRI Contrast Agent
TL;DR: The analysis of proton relaxivities reveals that, beside slow water exchange, internal flexibility is an important limiting factor for imaging magnetic fields.
174
Synthesis and Physicochemical Characterization of a New Gadolinium Chelate: The Liver-Specific Magnetic Resonance Imaging Contrast Agent Gd-EOB-DTPA
H. Schmitt-Willich,M. Brehm,Ch. L. J. Ewers,Günther Michl,A. Müller-Fahrnow,Orlin Dr Petrov,J. Platzek,Bernd Radüchel,Detlev Sülzle +8 more
TL;DR: The kinetics of isomerization of the isolated diastereomers-as dependent on pH and temperature-has been investigated, and thus, the activation energy for the interconversion of these isomers has been estimated to be 75.3 kJ mol(-1).
122
Physicochemical Characterization of MS‐325, a New Gadolinium Complex, by Multinuclear Relaxometry
Robert N. Muller,Bernd Radüchel,Sophie Laurent,Johannes Platzek,Corinne Piérart,Peter Mareski,Luce Vander Elst +6 more
TL;DR: The physicochemical characterization of MS-325, a new derivative of Gd-DTPA, was carried out in various media Water solution, protein-containing solution, phosphorylated metabolites solution, and Zn2+-based solution.
122
Pre-clinical evaluation of gadobutrol: a new, neutral, extracellular contrast agent for magnetic resonance imaging
Hubert Dr Vogler,Johannes Platzek,Gabriele Schuhmann-Giampieri,Thomas Frenzel,Hanns-Joachim Weinmann,Bernd Radüchel,Wolf-Rüdiger Press +6 more
TL;DR: In preliminary imaging experiments, gadobutrol caused high enhancement in different lesions (cerebral infarct, brain tumor) of the rat and tripling of the typical clinical dose of 0.1 mmol/kg was shown to provide additional diagnostic gain in lesions of this type.
116
Gadofluorine 8: initial experience with a new contrast medium for interstitial MR lymphography
TL;DR: Gadofluorine 8 is an innovative contrast agent that can distinguish between normal and tumorous lymph nodes in interstitial MR lymphography.
67