Bernd Kitze
University of Göttingen
26 Papers
326 Citations
Bernd Kitze is an academic researcher from University of Göttingen. The author has contributed to research in topics: Multiple sclerosis & Interferon beta-1b. The author has an hindex of 16, co-authored 26 publications. Previous affiliations of Bernd Kitze include Max Planck Society & Kagoshima University.
Chat about Author
Papers
Interferon-beta-1 b decreased matrix metalloproteinase-9 serum levels in primary progressive multiple sclerosis.
Maryna Yushchenko,Michael Mäder,Ercan Elitok,Andreas Bitsch,Alexander Dressel,Hayrettin Tumani,Timon Bogumil,Bernd Kitze,Sigrid Poser,Frank Weber +9 more
TL;DR: The suppression of MMP-9 by IFN-β1b indicates that this drug is immunomodulatory active in PPMS patients, and further studies are necessary to test if IFn-β exerts a beneficial effect in PP MS.
48
Diversity of intrathecal antibody synthesis against HTLV-I and its relation to HTLV-I associated myelopathy.
Bernd Kitze,Koichiro Usuku,Shuji Izumo,Minoru Nakamura,Hiroshi Shiraki,Shinji Ijichi,Shinji Yashiki,Toshinobu Fujiyoshi,Shunro Sonoda,Mitsuhiro Osame +9 more
TL;DR: The intrathecal antibody synthesis against several HTLV-I determinants may represent a pathogenic immune response in HAM/TSP and is possibly related to the infiltration of virus-infected T-cells in the spinal cord.
35
Human CD4+ T lymphocytes recognize a highly conserved epitope of human T lymphotropic virus type 1 (HTLV-1) env gp21 restricted by HLA DRB1*0101
Bernd Kitze,K. Usuku,Yoshihisa Yamano,Shinji Yashiki,Minoru Nakamura,Toshinobu Fujiyoshi,S. Izumo,M. Osame,Shunro Sonoda +8 more
TL;DR: Analysis of the CD4+ T lymphocyte response against eight synthetic peptides of HTLV‐1 envelope (env) glycoprotein gp21 found that it might exert either stimulating immunological or immunosuppressive effects in HT LV‐1‐infected individuals, depending on the level of its expression and the presence of HLA DRB1*0101.
32
Apheresis in treatment of acute inflammatory demyelinating disorders
TL;DR: Analysis of 140 adult patients treated with PE or IA in steroid refractory multiple sclerosis or neuromyelitis optica affirm previous findings showing no significant difference in efficacy and treatment safety.
26
Characterization of a unique T-cell clone established from a patient with HAM/TSP which recognized HTLV-I-infected T-cell antigens as well as spinal cord tissue antigens.
Masahiro Nagai,Shinji Yashiki,Toshinobu Fujiyoshi,Chihaya Fujiyama,Bernd Kitze,Shuji Izumo,Mitsuhiro Osame,Shunro Sonoda +7 more
TL;DR: Results indicated that HAM/TSP CD4+ T-cells were polyclonally activated by HTLV-I infection and antigenic stimulation, and the T-cell repertoire shaped by HT LVI infection included T- cells which recognized HT LVII-infected T- cell antigens as well as spinal cord antigen in particular.
23