Bernard Têtu
Laval University
6 Papers
22 Citations
Bernard Têtu is an academic researcher from Laval University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 6, co-authored 6 publications.
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Papers
Spatial genomic heterogeneity within localized, multifocal prostate cancer
Paul C. Boutros,Paul C. Boutros,Michael Fraser,Nicholas J. Harding,Richard de Borja,Dominique Trudel,Emilie Lalonde,Emilie Lalonde,Alice Meng,Pablo H. Hennings-Yeomans,Andrew McPherson,Veronica Y. Sabelnykova,Amin Zia,Natalie S. Fox,Natalie S. Fox,Julie Livingstone,Yu Jia Shiah,Jianxin Wang,Timothy Beck,Cherry Have,Taryne Chong,Michelle Sam,Jeremy Johns,Lee Timms,Nicholas Buchner,Ada Wong,John D. Watson,Trent T. Simmons,Christine P'ng,Gaetano Zafarana,Francis Nguyen,Xuemei Luo,Kenneth C. Chu,Stephenie D. Prokopec,Jenna Sykes,Alan Dal Pra,Alejandro Berlin,Andrew M.K. Brown,Michelle Chan-Seng-Yue,Fouad Yousif,Robert E. Denroche,Lauren C. Chong,Gregory M. Chen,Esther Jung,Clement Fung,Maud H.W. Starmans,Hanbo Chen,Shaylan K. Govind,James R. Hawley,Alister D'Costa,Melania Pintilie,Daryl Waggott,Faraz Hach,Philippe Lambin,Lakshmi Muthuswamy,Colin Cooper,Rosalind A. Eeles,David E. Neal,David E. Neal,Bernard Têtu,Cenk Sahinalp,Lincoln Stein,Neil E. Fleshner,Sohrab P. Shah,Colin Collins,Colin Collins,Thomas J. Hudson,John Douglas Mcpherson,Theodorus van der Kwast,Robert G. Bristow +69 more
TL;DR: A new recurrent amplification of MYCL is identified and validated, which is associated with TP53 deletion and unique profiles of DNA damage and transcriptional dysregulation, and this data represents the first systematic relation of intraprostatic genomic heterogeneity to predicted clinical outcome.
Physical activity, mammographic density, and age-related lobular involution among premenopausal and postmenopausal women.
TL;DR: Physical activity's effect on mammographic density or age-related lobular involution may mediate, in part, its protective effect against breast cancer.
25
Prognostic significance of TIMP-2, MMP-2, and MMP-9 on high-grade serous ovarian carcinoma using digital image analysis ☆
Patrice Desmeules,Dominique Trudel,Stéphane Turcotte,Jennifer Sirois,Marie Plante,Jean Grégoire,Marie-Claude Renaud,Michèle Orain,Bernard Têtu,Isabelle Bairati +9 more
TL;DR: In a homogeneous cohort of women with HGSC, increased MMP-9 tissue expression, as assessed by automated immunostaining quantification, was associated with a higher risk of death.
23
The UGT2B28 Sex-steroid Inactivation Pathway Is a Regulator of Steroidogenesis and Modifies the Risk of Prostate Cancer Progression
Anaïs Belledant,Hélène Hovington,Luciana Garcia,Patrick Caron,Hervé Brisson,Lyne Villeneuve,David Simonyan,Bernard Têtu,Yves Fradet,Louis Lacombe,Chantal Guillemette,Éric Lévesque +11 more
TL;DR: The role of UGT2B28 as a regulator of steroidogenesis is uncovered and underscores the interconnectivity among the steroid-inactivation capacity of cancer cells, hormone levels, disease characteristics, and the risk of cancer progression.
Impacts of a Large Decentralized Telepathology Network in Canada.
TL;DR: The findings show that no service disruptions were recorded in hospitals without pathologists following the deployment of telepathology, and Telepathology was perceived by respondents as having positive impacts on the remote hospitals' ability to retain and recruit surgeons.